摘要
邻苯二甲酸丁基苄酯(BBP)是邻苯二甲酸酯的一种,作为常用的增塑剂和溶剂,广泛应用于医疗、化工、食品、装修材料等产品,并在环境介质及人体中广泛检出.BBP被认为具有类雌激素作用,具有一定的生殖发育毒性.本文主要对BBP的代谢暴露水平、BBP及其主要代谢产物在雄性生殖发育毒性方面的研究进展进行了综述.
Butyl benzyl phthalate(BBP)is one member of phthalates(PAEs),which are used as plasticizers,solvent sand stabilizers in industry,medicine,building and consumer products.The widespread use of PAEs contributes to their omnipresent detection in the environment and human beings.BBP has been reported to be one of the homologous estrogen chemicals and it can induce reproductive and developmental toxicity.The present paper mainly reviews the exposure levels of BBP,male reproductive and developmental toxicity of BBP and its main metabolites.
出处
《中国科学:生命科学》
CSCD
北大核心
2016年第1期113-119,共7页
Scientia Sinica(Vitae)
基金
国家自然科学基金(批准号:21477127)资助
关键词
邻苯二甲酸丁基苄酯
雄性生殖毒性
发育毒性
butyl benzyl phthalate(BBP)
male reproductive toxicity
developmental toxicity