摘要
目的:探讨不同听力分期梅尼埃病患者前庭肌源诱发电位的特征及临床意义。方法:纳入2015-01-2015-07期间就诊于第二军医大学眩晕诊治中心的79例单侧梅尼埃病患者,按听力分期分为轻度听力受损组41例(听力1期、2期)、中重度听力受损组38例(听力3期、4期),同时纳入正常对照组20例,在发作间期行颈肌前庭诱发肌源性电位(C-VEMP)检查。结果:C-VEMP引出率在轻度听力受损组与正常对照组间差异无统计学意义,在中重度听力受损组与轻度听力受损组及正常对照组间差异有统计学意义(P<0.05)。P1、N1潜伏期在轻度听力受损组、中重度听力受损组和正常对照组间差异无统计学意义。P1-N1振幅以及振幅不对称比在轻度听力受损组与正常对照组间差异无统计学意义,中重度听力受损组与正常对照组及轻度听力受损组间差异有统计学意义(P<0.05)。结论:随着梅尼埃病患者听力受损程度的加重,患者球囊功能损伤也随之加重。
Objective：Our goal was to find whether inreversible function damage of saccule was exist and correlated in Meniere′s patients with different audition.Method：Senenty-nine patients with unilateral Meniere′s disease,who visited the Dizziness Diagnosis and Treatment Centre of the Second Military Medical University from January to July in 2015 were included.They were grouped as slightly audition damage group（41cases）,mildly-severely audition damage group（38cases）.Meanwhile 20 normal controls underwent the research.The cervical vestibular evoked myogenic potentials were conducted in symptom free period.Result：There was no significant difference of the C-VEMP inducing rate between slightly audition damage group and normal control group.While a statistically difference showed between mildly-severely audition damage group and normal control group or slightly audition damage group.P1,N1 latency had no statistically difference between three groups.The P1-N1 amplitude and asymmetric ratio had no difference between slightly audition damage group and normal control group,but had a statistically difference between mildly-severely audition damage group and slightly audition damage group,normal control group.Conclusion：The function of saccule in Meniere′s patients decreased with the aggravation of audition damage.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2016年第1期9-12,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
梅尼埃病
听力
颈肌前庭诱发肌源性电位
Ménière disease
audition
cervical vestibular evoked myogenic potentials
