摘要
目的:探讨中药注射剂溶媒类型、滴速与中药注射剂不良反应(ADR)之间的相关性。方法:选取ADR患者50例,全面系统分析患者基础资料与临床资料,统计、分析不良反应表现、原因。结果:56%患者因滴速过快发生ADR,32%患者因溶媒不当发生ADR,8%患者合并用药不当发生ADR,4%患者超剂量用药发生ADR,2%患者用药过久发生ADR,其中滴速过快、溶媒不当是本组患者中药注射剂使用中ADR发生的主要危险因素(P<0.05);皮肤及附件反应、呼吸系统反应是中药注射剂使用中最常见的ADR反应(P<0.05)。结论:滴速控制不当、溶媒类型选择错误会直接引发多种ADR表现。
Objective： To explore the correlation between TCM injection solvent type and dripping speed and adverse reactions（ ADR）. Methods： Fifty patients with ADR were chosen and their basic data and clinical data were systematically were collected and analyzed to find out the manifestations and causes of ADR. Results： Among the studied cases,65% of them had ADR due to fast dripping speed; 32% due to improper solvents; 8% due to improper combined drug-use; 4% due to over-dosage of drug; 2%due to long-time drug-use. And fast dripping speed and improper solvents were the main dangerous factors leading to ADR（ P〈0. 05）. Conclusion： Skin and its appendages reactions,and respiratory system were the most common ADR reactions in using TCM injections.
出处
《河南中医》
2015年第12期3200-3202,共3页
Henan Traditional Chinese Medicine
基金
上海市财政厅资助项目[编号:沪财工(2009)214号]
关键词
中药注射剂
溶媒
滴速
不良反应
TCM injections
solvents
dripping speed
adverse reactions
