摘要
目的基于2007年发表在《中国实用眼科杂志》上的新的Eales病的分期系统，探讨Eales病所在分期与视力预后的关系。方法在之前新的Eales病分期基础上，详细记录来院复查的62例Eales病患者的视力、眼压、眼底情况。这项研究的起止时间为2009年2月至2014年12月。之前所有患眼都曾被按照新的分期系统予以准确地记录。Ⅰ期：炎症期：小静脉和大静脉的血管周围炎，伴有视网膜浅层出血。Ⅱ期：缺血期：毛细血管无灌注，视盘和（或）视网膜的新生血管。Ⅲ期：增殖期：纤维血管增殖和玻璃体出血。Ⅳ期：并发症期：牵拉性或联合性视网膜脱离（牵拉性合并孔源性），黄斑前膜，新生血管性青光眼，并发性白内障。复查时，患者的视力被分为以下四级：Ⅰ级，〈0．1；Ⅱ级，0．2—0．4；Ⅲ级，0．5—0．9；Ⅳ级大于1．0。所有患眼都曾接受口服药物、激光光凝或玻璃体切除手术。使用配对t检验和Wilcoxon符号秩和检验作为统计方法。结果玻璃体出血是最常见的临床表现。Ⅰ-Ⅳ期患者的视力均有不同程度的改善。被随访的患者的视力变化范围为0．05-1．2。Ⅰ～Ⅳ期患者的视力治疗前后相比，差异有统计学意义（P〈0．05）。结论按照新的分期系统，Eales病患者经过口服药物、激光光凝或玻璃体切除手术后，视力有了明显的提高。此项研究对于Eales病的基础研究和临床治疗都会有一定的影响。
Objective To evaluate the visual outcome in Eales disease, based on a new classifi- cation system, for the first time. Methods Sixty-two consecutive cases of Eales＇ disease were included. All the eyes were staged according to the new classification： Stage 1 was periphlebitis of small and large caliber vessels with superficial retinal haemorrhages. Stage 2 was capillary non perfusion and neovascularization elsewhere/of the disc. Stage 3 was classified as fibrovascular proliferation and vitreous haemorrhage. Stage 4 was traction/combined rhegmatogenous retinal detachment, macular epiretinal membranes, neovascular glaucoma, complicated cataract. All the cases were managed by medical therapy, photocoagulation and/or vitreoretinal surgery. Visual acuity was converted into deci- mal scale, denoting 20/20=1 and 20/800=0.01. Paired t-test/Wilcoxon signed-rank tests were used for statistical analysis. Results Vitreous hemorrhage was the commonest presenting feature. Statistically significant improvement in visual acuities was observed in most of all the stages of the disease. Conclusions Significant improvement in visual acuities is observed in the majority of stages of Eales＇ disease following treatment. This study adds further to the little available evidences of treatment effects in literature and may have effect on patient care and health policy in Eales＇ disease.
出处
《中国实用眼科杂志》
2015年第12期1337-1340,共4页
Chinese Journal of Practical Ophthalmology
