摘要
目的 探讨去分化软骨肉瘤的临床表现、影像学、病理学特点及分析.方法 选取2002～2014年间确诊去分化软骨肉瘤12例,对其临床表现、放射学改变、病理形态学资料进行回顾性分析.结果 男8例,女4例,年龄范围在21～63岁,平均年龄48岁,发病部位为股骨4例、胫骨3例、肱骨2例、骨盆1例、肩胛骨1例、掌骨1例;主要临床症状为疼痛、肿胀,局部可触及的肿块,1例患者因病理性骨折就诊.去分化软骨肉瘤表现为双重形态特征的恶性肿瘤,大体中央型多于周围型,组织学由分界清楚的高分化软骨性肿瘤和高级别间变性肉瘤构成.结论 去分化软骨肉瘤较少见,临床结合影像及组织病理形态特征对去分化软骨肉瘤的诊断及治疗有重要意义.
Objective To investigate dedifferentiated chondrosarcoma of clinical manifestations, imaging, pathological features and analysis. Methods Selected from 2002 to 2014 dedifferentiated chondrosarcoma 12 cases, the clinical manifestations, radiological change, pathological data were retrospectively analyzed. Results 8 were males and 4 females, age range 21-63 years, mean age 48 years, the site of femur was 4 cases, tibia 3 cases, humerus 2 cases, pelvis 1 case, scapula 1 case, metacarpal 1 case; clinical symptoms were pain, swelling, local palpable mass, 1 case were treated because of pathological fracture. Dedifferentiated chondrosarcoma showed morphological features of malignancy double roughly central than peripheral, histologic score of the clear boundaries between cartilage tumors and sarcomas constitute a high-level variability. Conclusion Dedifferentiated chondrosarcoma is rare, clinical imaging and pathological morphology of dedifferentiated chondrosarcoma diagnosis and treatment is important.
出处
《中华临床医师杂志（电子版）》
CAS
2015年第23期36-38,共3页
Chinese Journal of Clinicians(Electronic Edition)
关键词
软骨肉瘤
去分化
放射学
病理学
Chondrosarcoma
Dedifferentiated
Radiology
Pathology
