摘要
目的探讨去分化软骨肉瘤的临床、影像学及病理学特点。方法收集11例去分化软骨肉瘤患者的临床及影像资料,对组织进行病理分析。结果患者以男性多见(7/11),平均年龄57.1岁,肿瘤多位于长管状骨及骨盆。影像学显示广泛的骨质破坏,病灶内可有钙化或骨化,病理性骨折3例。眼观:病理软骨成分常位于骨内,去分化肉瘤成分主要位于骨外。镜下包括高分化软骨肉瘤和低分化间叶源性肉瘤两种成分。随访材料中6例死亡,平均存活14个月。结论去分化软骨肉瘤检:呈少见的的软骨肉瘤亚型,去分化类型多样,只有加深对其的认识,才能提高诊断的准确率。
Purpose To investigate the clinical,imaging and pathologic characteristics of dedifferentiated chondrosarcoma.Methods The clinical and pathological data were reviewed in 11 cases of dedifferentiated chondrosarcoma.Results Most of these patients were male （7/11）.The mean age was 57.1 years.Most tumors were located in the long bone and pelvis.Imaging showed that bones were extensively destroyed.There was calcification or ossification on focus of infection.The gross specimen showed that cartilage component was located within bone and dedifferentiated sarcoma was found out of the bone.Microscopically,well differentiated chondrosarcoma and poorly differentiated sarcoma components were observed.Six patients died and the average survival time was 14 months.Conclusions Dedifferentiated chondrosarcoma is an unusual subtype of chondrosarcoma with pleomorphic alterations.Further understanding the pathologic features of the tumor is important to increase the accurancy of diagnosis.
出处
《临床与实验病理学杂志》
CAS
CSCD
北大核心
2010年第1期81-83,共3页
Chinese Journal of Clinical and Experimental Pathology
关键词
软骨肉瘤/病理学
去分化
影像
chondrosarcoma/pathology
dedifferentiated
imaging
