摘要
目的:了解我院住院患者质子泵抑制剂(PPI)的使用情况,为临床合理使用该类药物提供参考。方法:采用回顾性调查方法,利用医院信息HIS系统,统计2014年住院患者和使用PPI的人数、药品金额等信息。然后从PPI使用率排名前十位的科室中随机抽取500份病历(50份/科室),针对适应证、药物选择、给药时机、剂量、频率、给药途径、溶媒、联合用药及疗程等信息进行汇总并分析。结果:全院108 300例患者中PPI使用率为35.59%,药占比4.49%。PPI使用人次和销售金额均以注射用奥美拉唑居首。500份抽样病历中,不合理用药病历308份(61.60%),不合理用药现象主要包括无适应证用药、给药途径及频次不适宜、疗程过长等。结论:我院PPI的使用仍存在不合理现象,建议临床上在使用PPI类药物时应权衡利弊,规范用药,以降低患者的用药风险。
Objective： To investigate the use of proton pump inhibitor（PPI） in inpatients and provide the references for rational drug use in clinic. Methods： The hospital information system（HIS） was used to count the total number of hospitalization, the use times of PPI and sales amount of drugs in 2014 by retrospective investigation. Then 500 medical records（50 cases per department） were extracted randomly from the top 10 departments in terms of the use of PPI and the rationality of PPI use in respect of indication, drug selection, timing, dosage, frequency, administration route, menstruum, drug combination and course was analyzed. Results： In 108 300 records, the percent of using PPI was 35.59%, the amount of sales of PPIs accounted for 4.49% of the total amount of drug sales. The most use times and sales amount were omeprazole for injection in PPIs. The numbers of irrational PPI use were 308（61.60%） in 500 sampling medical records. Unreasonable phenomena included non-indication, unsuitable administration route, unsuitable frequency and long duration of medication. Conclusion： There were many irrational PPI uses in inpatients in our hospital. The clinicians should weigh pros and cons, and normalize administration of PPIs so as to reduce the drug-induced risks.
出处
《中国药物应用与监测》
CAS
2015年第6期372-375,共4页
Chinese Journal of Drug Application and Monitoring
基金
四川医事卫生法治研究中心资助项目(YF15-Y03)
