摘要
目的了解医院多重耐药菌(MDRO)检出情况,评价多学科合作管理MDRO的效果,为临床有效控制MDRO感染提供依据。方法比较某院2013年10月—2014年9月不同时段临床科室各项干预措施依从性及患者MDRO检出情况。结果 2013年第4季度,2014年第1、2、3季度4个不同时段各项控制措施依从率总体呈现上升趋势,差异均有统计学意义(均P<0.001)。2013年第4季度—2014年第3季度主要监测MDRO在同种菌中检出率:耐甲氧西林金黄色葡萄球菌(MRSA)分别为52.34%、45.45%、48.95%、26.25%;耐碳青霉烯类鲍曼不动杆菌(CRAB)分别为64.42%、63.07%、59.87%、43.09%;多重耐药铜绿假单胞菌(MDRPA)分别为42.11%、41.82%、29.33%、17.52%;MRSA、CRAB、MDRPA检出率总体呈现下降趋势,不同时段检出率比较,差异均有统计学意义(均P<0.001)。耐碳青霉烯类肠杆菌科细菌(CRE)、耐万古霉素肠球菌(VRE)检出率低(<5%),各时段比较,差异均无统计学意义(均P>0.05)。结论积极推行多学科合作MDRO管理模式,有利于降低MDRO的产生与传播。
Objective To investigate the detection of multidrug-resistant organisms（MDROs）in a hospital,evaluate the efficacy of multi-disciplinary team（MDT）on management of MDROs,and provide guidance for effective control on MDRO infection.Methods From October 2013 to September 2014,compliance to comprehensive intervention measures in clinical departments in different stages as well as detection of MDROs from patients were compared respectively.Results Compliance to comprehensive intervention measures showed an overall upward trend from the fourth quarter of 2013 to the first,second,and third quarters of 2014,difference was statistically significant（all P0.001）.From the fourth quarter of 2013 to the third quarter of 2014,the percentage of the major MDRO strains in the same species of bacteria were：methicillin-resistant Staphylococcus aureus（MRSA）52.34%,45.45%,48.95%,and 26.25% respectively;carbapenem-resistant Acinetobacter baumannii（CRAB）64.42%,63.07%,59.87%,and 43.09% respectively;multidrug-resistant Pseudomonas aeruginosa（MDRPA）42.11%,41.82%,29.33%,and 17.52% respectively;the detection rate of MRSA,CRAB,and MDRPA showed an overall downward trend,difference among different stages were statistically significant（all P0.001）.Detection rates of carbapenem-resistant Enterobacteriaceae（CRE）and vancomycin-resistant Enterococcus（VRE）were both low（5%）,difference among different stages were not statistically significant（all P0.05）.Conclusion MDT on management of MDROs is helpful for reducing the emergence and spread of MDROs.
出处
《中国感染控制杂志》
CAS
北大核心
2015年第12期846-848,共3页
Chinese Journal of Infection Control
关键词
多学科合作
多重耐药
多重耐药菌株
多重耐药菌管理
效果评价
医院感染
multi-disciplinary team
multidrug resistance
multidrug-resistant organism
management of multidrug-resistant organism
effect evaluation
healthcare-associated infection
