摘要
目的对比经皮椎体成形术（PVP）与保守治疗骨质疏松致椎体压缩性骨折的疗效差异。方法选取我院2009年7月~2014年7月收治的72例骨质疏松性椎体压缩性骨折患者作为研究对象,将所选患者随机分为研究组和对照组,研究组采用PVP术治疗,对照组采用卧床休息、药物等保守治疗,使用视觉模拟疼痛评分（VAS）评价疼痛情况,Oswestry功能障碍指数问卷表（ODI）评价肢体、行为功能障碍,综合比较两组患者手术前后椎体前缘高度、后凸Cobb角改善情况、VAS、ODI评分情况及椎体骨折再发风险的差异。结果手术后研究组患者椎体前缘高度、后凸Cobb角改善情况优于对照组（P〈0.05）;术后3d、1个月、3个月,研究组VAS评分、ODI评分均低于对照组（P〈0.05）;研究组椎体骨折再发风险为13.9%,与对照组的16.7%比较,差异无统计学意义（P〉0.05）。结论经皮椎体成形术治疗骨质疏松性椎体压缩性骨折效果确切,可有效缓解术后疼痛,改善肢体功能,不增加术后再发椎体骨折的风险,优于保守治疗,值得临床推广使用。
Objective To compare the effects of PVP and conservative for osteoporotic vertebral compression fractures. Methods 72 cases of osteoporotic vertebral compression fractures in our hospital were randomly divided into research group and control group, each were 36 cases. Research group were treated with PVP, while control group were treated with conservative treatment. The pain was measured by visual analog pain scale（VAS） score, while limb and behavioral dysfunction was measured by oswestry disability index questionnaire（ODI）.The vertebroplasty vertebral height, Cobb＇s angle, VAS and ODI scores before and after surgery and risk of re-fracture of two groups were compared. Results After surgery, the ertebroplasty vertebral height and Cobb＇s angle of research group were better than control group（P〈0.05）.Postoperative 3d,1 month and 3 months,VAS and ODI scores of research group were lower than control group（P〈0.05）.The risk of re-fracture of research group was 13.9%, which had no significant difference with 16.7% of control group（P〈0.05）. Conclusion PVP for osteoporotic vertebral compression fractures has exact effects. It can effectively relieve pain and improve physical function, does not increase the risk of refracture. It＇s better than conservative treatment. It＇s worthy of clinical widely used.
出处
《中国医药科学》
2015年第20期112-114,共3页
China Medicine And Pharmacy
基金
广东省云浮市医药卫生科研立项项目(2014B24)
关键词
经皮椎体成形术
保守
骨质疏松
椎体压缩性骨折
Percutaneous vertebroplasty
Conservative
Osteoporosis
Vertebral compression fractures
