摘要
目的研究医院铜绿假单胞菌感染特点及其耐药性,为临床合理用药提供依据。方法采用回顾性调查方法,对某医院住院患者送检病原学标本中铜绿假单胞菌分离鉴定和药敏试验结果进行统计分析。结果从该医院住院患者送检的病原学标本中共检出铜绿假单胞菌258株,2011-2013年度检出株数依次为68株、82株和108株,主要分离自痰液标本,其次为脓液。临床分离的铜绿假单胞菌对临床常用16种抗菌药物普遍耐药,对多数头孢类抗菌药物和氨苄西林耐药率超过50%,仅对亚胺培南和美落培南耐药率较低,对氨曲南耐药率已超过30%。结论该医院临床分离的铜绿假单胞菌耐药情况严重,应根据药敏结果合理用药。
Objective To study the characteristics and drug resistance of Pseudomonas aeruginosa（ PAE） infection,provide basis for the clinical use of drugs. Methods A retrospective study was used to analyze the results of identification and susceptibility test of PAE isolated from inpatients specimen. Results 258 strains of PAE were isolated from inpatients specimen,and the number of 2011,2012,2013 was 68,82 and 108 respectively. PAE mainly isolated from sputum specimens,followed by pus. The drug resistance of PAE to 16 kinds of antibiotics was generally high. The resistant rate of PAE to most cephalosporins and ampicilin were over 50%,but the resistant rate to imipenem was low. The resistant rate of PAE to aztreonam was over 30%. Conclusion The drug resistance status of PAE was serious in this hospital,clinical doctors should use drug rationally base on susceptibility results.
出处
《中国消毒学杂志》
CAS
北大核心
2015年第12期1194-1195,1198,共3页
Chinese Journal of Disinfection
关键词
铜绿假单胞菌
医院感染
抗菌药物
耐药性
Pseudomonas aeruginosa
nosocomial infection
antimicrobial agents
drug resistance
