摘要
目的对布比卡因（BUP）单用及与苏芬太尼（SUF）合用对剖宫产产妇术中寒战和牵拉痛的改善效果进行观察并探讨。方法选择接受剖宫产手术的产妇96例，采用随机数字法将产妇分为观察组和对照组，观察组48例给予 BUP 联合 SUF 进行麻醉；而对照组48例则仅给予 BUP 麻醉。统计两组产妇术中寒战和牵拉痛情况，并比较两组不良反应发生情况。结果观察组的感觉阻滞起效时间和持续时间为（1．7±0．5）min 和（126．2±9．5）min，而对照组为（2．0±0．4）min 和（79．1±11．0）min，两组比较，差异有统计学意义（t ＝2．295、15．88，均 P ＜0．05）。观察组产妇术中寒战和牵拉痛发生例数为2例和3例，对照组为9例和10例，两组差异有统计学意义（χ2＝5．031、4．360，均 P ＜0．05）；而在局麻药毒性反应方面，两组均没有发生。在麻醉的综合疗效上，观察组产妇麻醉效果较对照组更为明显，观察组麻醉率为97．9％（47／48），对照组为83．3％（40／48），两组麻醉效果比较，差异有统计学意义（χ2＝4．414，P ＜0．01）。结论BUP 联合 SUF 在剖宫产手术中麻醉效果较好，产妇寒战和疼痛情况显著改善，且术后不良反应更少。
Objective To observe and explore the effect of bupivacaine （BUP）single use or combined with sufentanil （SUF）for pregnant woman in caesarean operation with chills and pain.Methods 96 pregnant women with caesarean section were selected,they were randomly divided into observation group and control group by random num-ber method,each group with 48 cases.Patients in the observation group accepted BUP combined with SUF treatment, while the control group only received BUP treatment.The intraoperative and postoperative data of maternal chills and dragging pain,and the incidence of adverse reactions were compared between the two groups.Results The sensory block onset time and duration of the observation group were （1 .7 ±0.5）min and （1 26.2 ±9.5）min,which in the control group were （2.0 ±0.4）min and （9.1 ±1 1 .0）min,the differences between the two groups were statistically significant （t =2.295,1 5.88,all P 〈0.05）.For chills and stretch of pregnant women,the number of the observation group were 2 casesand 3cases,which in the control group were 9cases and 1 0cases,the differences between the two groups were statistically significant （χ2 =5.031 ,4.360,all P 〈0.05）.No patient had toxicity of local anesthetics between two groups.Total anesthesia effective rate of the observation group was 97.9%,which of the control group was 83.3%,the total anesthesia effect of the observation group was better than the control group （χ2 =4.41 4,P 〈0.01 ）. Conclusion BUP combined with SUF treatment has significant effect for pregnant women in caesarean operation,as well as can significantly relieve the pregnant women＆#39;chills and pain.
出处
《中国基层医药》
CAS
2015年第24期3681-3684,共4页
Chinese Journal of Primary Medicine and Pharmacy
