摘要
目的:探讨改良抗酸染色法在儿童结核性脑膜炎诊断中的价值。方法:应用BACTEC MGIT 960培养法、离心涂片法、改良抗酸染色法同时对30份临床诊断为结核性脑膜炎的儿童的脑脊液标本进行检测。结果:BACTEC MGIT 960培养法、离心涂片法及改良抗酸染色法的阳性率分别为13.3%(4/30)、3.33%(1/30)、56.7%(17/30)。改良抗酸染色法与BACTEC MGIT 960培养法、离心涂片法比较差异均有统计学意义(P<0.005)。结论:改良抗酸染色法诊断儿童结核性脑膜炎阳性率明显提高,值得临床推广应用。
Objective: To assess the clinical value of applying modified Ziehl-Neelsen stain to diagnosis of tuberculous meningitis in children. Methods:The cerebrospinal fluid( CSF) was detected in 30 cases confirmed clinically as tuberculous meningitis by BACTEC MGIT 960 culture system,centrifuged smear test and modified Ziehl-Neelsen stain,respectively,and the results were compared for the positive accuracy. Results: The positive rate by BACTEC MGIT 960 culture system,centrifuged smear test and modified Ziehl-Neelsen stain was 13. 3%( 4 /30),3. 33%( 1 /30) and 56. 7%( 17 /30),respectively,and the difference was significant( P〈0. 005). Conclusion: The modified Ziehl-Neelsen stain can be more sensitive in rapid diagnosis of tuberculous meningitis in children,and is worthy of wider clinical recommendation.
出处
《皖南医学院学报》
CAS
2015年第6期568-570,共3页
Journal of Wannan Medical College