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湿润烧伤膏联合高压氧治疗糖尿病足溃疡的临床疗效及机制 被引量:2

Clinical Efficacy and Mechanism of MEBO Combined with Hyperbaric Oxygen For Patients with Diabetic Foot Ulcers
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摘要 目的分析湿润烧伤膏(MEBO)联合高压氧治疗糖尿病足溃疡的临床效果,并探讨其作用机制。方法将该院于2009年6月—2014年6月收治的50例糖尿病足溃疡患者随机分为2组,观察组使用MEBO联合高压氧进行治疗,对照组给予常规换药。于治疗后记录两种方法对溃疡的治疗21 d后创面愈合率、治愈时间、换药疼痛程度等指标。结果在糖尿病足治疗效果、治愈时间、换药疼痛程度等方面观察组组均优于对照组(P<0.05)。结论 MEBO联合高压氧治疗糖尿病足溃疡临床疗效优于对照组。其机制可能与保持创面生理性湿润环境、改善创面微循环,减轻溃疡局部缺氧状态有关。 Objective To observe the clinical efficacy and mechanism of MEBO combined with hyperbaric oxygen in the treatment of patients with diabetic foot ulcers.Methods 50 patients with diabetic foot ulcers from 2009 June to 2014 June were divided into2 groups.MEBO combined with hyperbaric oxygen therapy was performed in the observation group,while conventional dressing therapy was used in the control group.Wound healing rate,healing time,pain in dressing change under the two methods 21 day after the treatment were recorded.Results In the treatment of diabetic foot ulcer,curative effect,healing time,pain in dressing change of the observation group were better than those of the control group(P〈0.05).Conclusion MEBO Combined with Hyperbaric oxygen has better efficacy than the routine treatment.The mechanism may be related to maintaining physiological moist environment,improving the microcirculation of the wound,reducing ulcer local hypoxia state.
作者 王志东
出处 《中外医疗》 2015年第17期113-114,117,共3页 China & Foreign Medical Treatment
关键词 糖尿病足 湿润烧伤膏 高压氧 Diabetic Foot Ulcer MEBO Hyperbaric Oxygen
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