摘要
目的观察依托咪酯与咪达唑仑用于老年患者在麻醉诱导期对于无创心排量的影响。方法收集60个病例,ASA分级Ⅰ~Ⅱ级全身麻醉手术患者,开放外周静脉,随机分为依托咪酯(A)、咪达唑仑(B)两组,A组用依托咪酯诱导,剂量为0.15 mg/kg,复合靶控输注瑞芬太尼;B组用咪达唑仑诱导,剂量为0.1 mg/kg同样复合靶控输注瑞芬太尼,观察记录诱导前(T_0),诱导后(T_1)与插管即刻(T_2)、插管后1 min(T_3)、插管后3 min(T_4)的平均动脉压(MAP)、心率(HR)、心排血量(CO)、心排指数(CI)及外周阻力(SVR)。结果依托咪酯组T_1、T_2、T_3、T_4时的MAP、HR、CO、CI、SVR与诱导前相比,差异无统计学意义;咪达唑仑组T_1、T_2、T_3、T_4时的MAP、HR、CO、CI、SVR与诱导前相比差异有统计学意义。结论依托咪酯全身麻醉诱导后对老年患者血流动力学的影响与咪达唑仑相比较为平稳。
Objective To observe the older patients’ cardiovascular responses to the inducement of Remifentanil combined respectively with midazolam andetomidate.Methods ASA grade I^II Total 60 patients with gener anesthesia and open outer vein were selected and randomly divided into groups of etomidate （group A）and midazolam（group B）. Group A received TCI of Remifentanil and intravenou injection of etomidat, group B received TCI of remifentanil and intravenou injection of midazolam. A monitor was used to observe and record MAP, HR, CO,CI, and SVR separetedly at the time before anesthesia induction, the time after anesthesia induction, the time at intubation tube point, the time after intubation tube 1 and 3 min.Results There was no signiifcant changes of MAP, HR, CO,CI during T1, T2, T3, T4, and SVR in group A before and after the anesthesia induction, while in group B there was a significant decrease of MAP, HR, CO,CI during T1, T2, T3, T4, and SVR after the anesthesia inducement.Conclusion The inducement of etomidat gener anesthesia has smooth and steady effect on the elderly’s blood lfow dynamics than midazolam.
出处
《中国继续医学教育》
2015年第30期60-62,共3页
China Continuing Medical Education
基金
泉州市科委资助课题(编号:2009Z38)
