摘要
目的探讨氯沙坦联合卡托普利治疗肺心病心力衰竭的临床疗效。方法选取肺心病心力衰竭的患者142例,随机分为对照组和观察组,各71例。对照组应用氯沙坦口服治疗,每次50 mg,观察组应用氯沙坦和卡托普利联合治疗,氯沙坦钾片口服,每次50 mg,每天1次。卡托普利每次1片,每天2次。30 d后进行疗效比较观察。结果观察组显效32例(45.07%),有效36例(50.71%),无效3例(4.23%),总有效率为95.77%。对照组显效29例(40.85%),有效30例(42.25%),无效12例(16.90%),总有效率为83.10%。2组总有效率比较,差异有统计学意义(χ2=6.038,P=0.014)。结论应用氯沙坦联合卡托普利治疗肺心病心力衰竭,不仅可以提高治疗效果,而且可以明显减轻患者痛苦,值得临床推广应用。
Objective To investigate the effect of patients with pulmonary heart disease combined congestive heart failure treated by losartan and captopril. Methods 142 patients with pulmonary heart diseasecombined congestive heart failure were randomly divided into control group and observation group, each group was 71 eases. The control group were given losartan, while the observation group were given losartan and eaptopril. The effects of the two groups were compared after 30 days. Resu Its The effective treatment in 32 cases (45.07%), valid in 36 cases (50.71%), invalid in 3 cases (4.23%) in observation group, the total effective rate was 95.77%.The effective 29 cases (40.85%), valid in 30 cases (42.25%),invalid in 12 cases (16.90%) in control group, the total effective rate was 83.10%. was significant difference in effective rate between two groups (χ^2=6.038, P=-0.014). Conclusion Losartan and captopril in treatment of pulmonary heart disease combined congestive heart failure in treating can not only enhance the treatment effect, and can significantly reduce pain, and worthy of clinical application.
出处
《当代医学》
2015年第34期142-143,共2页
Contemporary Medicine
关键词
肺心病
心力衰竭
氯沙坦
卡托普利
Pulmonary heart failure
Congestive heart failure
Losartan
Captopril