摘要
目的探讨长脉宽1064nmNd：YAG激光治疗复发性中重度痤疮伴痤疮后红斑的临床疗效和安全性。方法选取20例复发性中重度痤疮伴痤疮后红斑患者，采用长脉宽1064nmNd：YAG激光，光斑直径6．0mm．能量25～30J／cm2，频率3．0Hz，脉宽20～40ms，治疗病变部位，治疗间隔1周，治疗8次，治疗前后拍照并对皮损进行计数，实验结束后行疗效分析比较。结果20例患者经过8次治疗，基本痊愈17例，显效3例，总有效率100％，皮损平均计数较治疗前有明显下降，治疗前后差异有统计学意义（P〈0．05）；同时皮肤质地较治疗前有改善，90％以上患者表示满意。早期炎性皮损的治疗效果优于红斑，二者的疗效差异有统计学意义（P〈0．05）。术后不良反应为暂时性红斑。结论长脉宽1064nmNd：YAG激光治疗中重度痤疮伴痤疮后红斑疗效确切，安全性高，无明显不良反应，是一种治疗痤疮和持久性痤疮后红斑安全、有效的新方法。
Objective To elucidate the efficacy and safety of long-pulsed 1064nm Nd：YAG laser in the treatment of moderate to severe acne complicated with post-acne erythema. Methods A total of 20 cases of moderate to severe acne complicated with post-acne erythema were recruited, who were treated with long-pulsed 1 064 nm Nd：YAG laser. The laser parameters were： 25 - 30 J/cmz, 3.0 Hz, 20 ～ 40 ms pulse duration, 6.0 mm spot size. All patients were treated once a week for 8 weeks. Pictures of acne lesions were taken and the numbers were recorded before and after treatment. Results Of all 20 cases, 17 were cured, and 3 were improved. The total effective rate was 100%. The number of ac- ne lesions was significantly reduced （ P 〈 0.05 ）. Meanwhile, the texture of the skin was improved, and more than 90% patients were satisfied. The treatment effect of early inflammatory lesions was better than that of acne erythema （ P 〈 0.05）. The side effect was transient erythema after treatment. Conclusions Long-pulsed 1 064 nm Nd： YAG laser is safe and effective in the treatment of moderate to severe acne with acne erythema. It is a new therapeutic approach for acne and persistent post-acne erythema.
出处
《山东大学学报（医学版）》
CAS
北大核心
2015年第11期85-88,共4页
Journal of Shandong University:Health Sciences
基金
山东省科技发展计划(2014GSF118124)
山东大学口腔医院医疗新技术启动基金项目(20140303)
