摘要
目的探讨Q开关1 064 nm激光联合长脉宽1 064 nm Nd:YAG激光治疗黄褐斑的临床疗效。方法选择深圳市龙华新区人民医院2015年2月-2016年1月收治的76例黄褐斑患者为研究对象,以随机数字表法分为观察组与对照组各38例,对照组接受Q开关1 064 nm激光治疗,观察组接受Q开关1 064 nm激光联合长脉宽1 064 nm Nd:YAG激光治疗,对两组患者治疗后疗效与黄褐斑皮损面积及严重指数(MASI)进行观察。结果观察组与对照组治疗后总有效率分别为94.74%、76.32%,差异有统计学意义(P<0.05);治疗前,两组患者MASI分值差异无统计学意义(P>0.05),治疗1个月、3个月、6个月时,两组患者MASI分值均呈下降趋势,观察组治疗后各时间段MASI分值均较对照组低,差异有统计学意义(P<0.05)。结论黄褐斑采用Q开关1 064 nm激光联合长脉宽1 064 nm Nd:YAG激光治疗效果显著,且效果稳定,安全性高,值得推广。
Objective To observe the clinical effects of Q switch 1064 nm laser combined with long pulse width 1064 nm Nd：YAG laser in the treatment of chloasma. Methods 76 patients with chloasma in Longhua District People＇s Hospital from February 2015 to January 2016 were selected and randomly divided into observation group and control group by random number table method,with 38 cases in each group. The control group treated with Q switch 1064 nm laser,while the observation group treated with Q switch 1064 nm laser combined with long pulse 1064 nm Nd：YAG laser. The clinical effect and lesion area and severity index（MASI）of melasma in the two groups were observed. Results The total effective rate of the observation group and the control group were 94.74% and 76.32%,the difference was statistically significant（P〈0.05）;Before treatment,there was no significant difference in MASI scores between the two groups（P〉0.05）. After treatment of 1 month,3 months and 6 months,the MASI scores of two groups were showed downward trend,and the MASI scores of each time period in the observation group after treatment were lower than those in the control group,the difference was statistically significant（P〈0.05）. Conclusion The effects of Q switch 1064 nm laser combined with long pulse width 1064 nm Nd：YAG laser in the treatment of chloasma are significant with the stable effect and high security,thus it is worthy to be promoted.
出处
《中国城乡企业卫生》
2017年第3期68-70,共3页
Chinese Journal of Urban and Rural Enterprise Hygiene
