期刊文献+

高敏C反应蛋白与肌钙蛋白在急性冠脉综合征中的应用分析 被引量:6

Application analysis of high-sensitivity C reactive protein and cardiac tro-ponin in acute coronary syndrome
下载PDF
导出
摘要 目的 探讨高敏C反应蛋白与肌钙蛋白浓度测定对急性冠脉综合征患者的临床意义。方法 选取2013年7月~2015年7月在本院治疗的90例急性冠脉综合征患者作为观察组,选取90例健康体检者作为对照组,观察两组的高敏C反应蛋白以及肌钙蛋白水平,同时比较不同心功能级别患者的高敏C反应蛋白与肌钙蛋白水平。结果 观察组的高敏C反应蛋白与肌钙蛋白水平显著高于对照组,差异有统计学意义(P〈0.05)。Ⅳ级心功能患者的高敏C反应蛋白与肌钙蛋白水平显著高于Ⅰ、Ⅱ、Ⅲ级心功能患者,差异有统计学意义(P〈0.05)。Ⅲ级心功能患者的高敏C反应蛋白与肌钙蛋白水平显著高于Ⅰ、Ⅱ级患者,差异有统计学意义(P〈0.05)。Ⅱ级心功能患者的高敏C反应蛋白与肌钙蛋白水平显著高于Ⅰ级心功能患者,差异有统计学意义(P〈0.05)。结论 高敏C反应蛋白及肌钙蛋白浓度检测对于急性冠脉综合征患者具有重要的临床诊疗意义,值得临床推广应用。 Objective To explore the clinical significance of detecting the level of high-sensitivity C reactive protein (hs-CRP) and cardiac troponin in acute coronary syndrome patients. Methods 90 patients with acute coronary syn- drome from July 2013 to July 2015 in our hospital were selected as the observation group,and 90 healthy persons were selected as the control group.The level of hs-CRP and cardiac troponin in two groups was observed,and the Fevel of hs- CRP and cardiac troponin in patients with different cardiac function was compared. Results The level of hs-CRP and cardiac troponin in the observation group was higher than that in the control group,with significant difference (P〈0.05). The level of hs-CRP and cardiac troponin in grade Ⅳ patients with cardiac function was higher than that in grade Ⅰ , Ⅱ, Ⅲ patients with cardiac function,with significant difference (P〈0.05).The level of hs-CRP and cardiac troponin in grade Ⅲ patients with cardiac function was higher than that in grade Ⅰ , Ⅱ patients with cardiac function,with signifi- cant difference (P〈0.05). The level of hs-CRP and cardiac troponin in grade Ⅱ patients with cardiac function was higher than that in grade Ⅰ patients with cardiac function,with significant difference (P〈0.05). Conclusion Detecting of the level of hs-CRP and cardiac troponin have important meaning for clinical diagnosis and therapy of acute coronary syndrome patients,it is worthy of clinical promotion and application.
出处 《中国当代医药》 2015年第31期54-56,共3页 China Modern Medicine
关键词 高敏C反应蛋白 肌钙蛋白 急性冠脉综合征 急性心肌梗死 High-sensitivity C reactive protein Cardiac troponin Acute coronary syndrome Acute myocardium infarction
  • 相关文献

参考文献16

二级参考文献118

共引文献112

同被引文献24

  • 1王临光,王海波,付强,李先进.急性冠脉综合症诊断中检测心肌肌钙蛋白I肌红蛋白及肌酸激酶同工酶及超敏C-反应蛋白的意义[J].河北医学,2006,12(1):1-3. 被引量:41
  • 2Apple FS, Collinson PO. Analytical characteristics of high - sensitivity cardiac troponin assays[J]. Clinical Chemistry,2012,58 ( 1 ) :54 - 61. 被引量:1
  • 3Apple FS,Ler R,Murakami MM. Determination of 19 cardiac troponin I and assay 99th percentile values from a conunon presumably healthy population[J]. Clinical Chemistry,2012,58 ( 11 ) :1574 - 1581. 被引量:1
  • 4Praco R, Kruk M, Jakubczak B, et al. Superior early diagnostic per- formance of a sensitive cardiac troponin assay as compared to a standard troponin test in the diagnosis of acute myocardial infarction [J]. Kardiologia Polska,2012,70(2) :131 -138. 被引量:1
  • 5Twerenbold R, Wildi K, Jaeger C, et al. Optimal cutoff levels of more sensitive cardiac troponin assays for the early diagnosis of myocardial infarction in patients with renal dysfunction[ J]. Circu- lation,2015,131 (23) :2041 - 2050. 被引量:1
  • 6Mueller M, Celik S, Biener M,et al. Diagnostic and prognostic per- formance of a novel high sensitivity cardiac troponin T assay com- pared to a contemporary sensitive cardiac troponin I assay in pa- tients with acute coronary syndrome[J]. Clinical Research in Car- diology,2012,101 (10) :837 - 845. 被引量:1
  • 7Cullen L,Mueller C ,Parsonage WA,et al. Validation of high sensitive troponin I in 2 hours diagnostic strategy to assess 30 day outcomes in emergency department patients with possible acute coronary syndrome [J].J Am Coil Cardiol,2013,62:1242 -1249. 被引量:1
  • 8Jaakkola K, Jalkanen S, Kaunism 16 K, et al .Vascular adhesion protein-l,intercellular adhesion molecule-land P-selectin mediate leukocyte binding to ischemic heart in humans. J Am Coll Cardiol,2000,36(1): 122-129. 被引量:1
  • 9邓永超,莫丽亚,唐喜春,黄彩芝,赖源.血清心肌肌钙蛋白I与超敏C反应蛋白检测在婴幼儿重症肺炎中的诊断价值[J].国际检验医学杂志,2010,31(3):288-289. 被引量:11
  • 10曾平原,唐前光.急性冠脉综合征患者血清高敏C反应蛋白及肌钙蛋白Ⅰ水平监测的意义[J].中国医疗前沿,2010,5(7):59-60. 被引量:4

引证文献6

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部