温度调节基因开关调控大肠杆菌发酵
Fermentation in recombinant Escherichia coli with thermo-regulated genetic switch
摘要
微生物作为细胞工厂,已被应用于许多同源及异源代谢产物的生产,包括发酵型产物(氨基酸、有机酸、有机醇)以及众多次级代谢产物的生产[1-4]。然而,其中多数代谢产物的过量合成会对细胞造成伤害,抑制细胞的生长或者使代谢流失衡[5-6]。
出处
《微生物学通报》
CAS
CSCD
北大核心
2015年第11期2270-2271,共2页
Microbiology China
关键词
L-丙氨酸
基因开关
大肠杆菌
发酵
代谢工程
L-alanine, Genetic switch, Escherichia coli, Fermentation, Metabolic engineering
参考文献10
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