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组织运动二尖瓣环位移自动追踪技术定量评估早期心尖肥厚型心肌病的收缩功能 被引量:5

Tissue motion tracking of mitral annular displacement in evaluation on left ventricular systolic function in patients with pre-apical hypertrophic cardiomyopathy
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摘要 目的应用组织运动二尖瓣环位移自动追踪(TMAD)技术测定二尖瓣环收缩期位移(MAD),探讨其在评估早期心尖肥厚型心肌病(PAHCM)患者左心室收缩功能中的临床应用价值。方法分别选择26例PAHCM患者、高血压左心室肥厚(HLVH)患者和健康自愿者。所有研究对象均经常规超声心动图检查并存储相应切面的二维图像,以双平面Simpson法测量左心室舒张末期容积(EDV)、左心室收缩末期容积(ESV)、每搏量(SV)以及左心室射血分数(LVEF)。应用QLAB 9.1工作站,自动获取二尖瓣环各位点相对于心尖处的收缩期峰值位移(SD),计算3个切面6个位点平均峰值位移。结果与正常对照组相比较,PAHCM组在各位点的SD以及6个位点平均峰值位移差异有统计学意义[(10.16±1.17)mm vs(13.09±1.25)mm,(9.03±1.35)mm vs(12.45±1.61)mm,(10.25±1.07)mm vs(12.53±1.29)mm,(10.54±1.01)mm vs(12.39±1.52)mm,(9.25±1.13)mm vs(13.09±1.75)mm,(9.95±0.83)mm vs(12.35±0.94)mm,(9.86±0.39)mm vs(12.65±0.68)mm,t=-8.74、-8.98、-6.92、-5.19、-9.37、-9.74、-18.02,P均<0.05]。与HLVH组比较,PAHCM组在后间壁、后壁、前间壁、前壁的SD以及6个位点平均峰值位移差异有统计学意义[(10.16±1.17)mm vs(8.42±1.28)mm,(10.25±1.07)mm vs(8.36±1.20)mm,(10.54±1.01)mmvs(8.84±1.08)mm,(9.95±0.83)mm vs(8.58±1.09)mm,(9.86±0.39)mm vs(8.50±0.46)mm,t=5.10、6.00、5.87、5.11、11.48,P均<0.05],而在侧壁、下壁的SD差异无统计学差异[(9.03±1.35)mm vs(8.30±1.27)mm,(9.25±1.13)mm vs(8.52±1.21)mm,t=2.25、2.27,P均>0.05]。与正常对照组比较,HLVH组在各位点的SD以及6个位点平均峰值位移差异有统计学意义[(8.42±1.28)mm vs(13.09±1.25)mm,(8.30±1.27)mm vs(12.45±1.61)mm,(8.36±1.20)mm vs(12.53±1.29)mm,(8.84±1.08)mm vs(12.39±1.52)mm,(8.52±1.21)mm vs(13.09±1.75)mm,(8.58±1.09)mm vs(12.35±0.94)mm,(8.50±0.46)mm vs(12.65±0.68)mm,t=-13.27、-10.34、-12.09、-9.71、-10.93、-13.35、-25.59,P均<0.05]。结论与LVEF比较,使用TMAD测定 Objective To investigate the value of left ventricular systolic function in patients with pre-apical hypertrophic cardiomyopathy(PAHCM) by tissue motion tracking of mitral annular displacement(TMAD). Methods 26 cases in each group of PAHCM, hypertensive left ventricular hypertrophy(HLVH) and healthy volunteers were selected respectively. All of the subjects were examined by conventional echocardiography and store two-dimensional image of corresponding section. Using biplane Simpson method to measure left ventricular end-diastolic volume(EDV), left ventricular end-systolic volume(ESV), stroke volume(SV) and left ventricular ejection fraction(LVEF). Mitral annulus systolic peak displacement(SD) and average peak displacement of six sites in three sections were automatic measured in QLAB 9.1 workstation. Results Compared with the control group, the difference was statistically significant at all points of SD and the average peak displacement in PAHCM group [(10.16±1.17) mm vs(13.09±1.25) mm,(9.03±1.35) mm vs(12.45±1.61) mm,(10.25±1.07) mm vs(12.53±1.29) mm,(10.54±1.01) mm vs(12.39±1.52) mm,(9.25±1.13) mm vs(13.09±1.75) mm,(9.95±0.83) mm vs(12.35±0.94) mm,(9.86±0.39) mm vs(12.65±0.68) mm, t=-8.74,-8.98,-6.92,-5.19,-9.37,-9.74,-18.02, P〈0.05]. Compared with HLVH group, the difference was statistically significant at SD of inferoseptal, posterior wall, anteroseptal, anterior wall and the average peak displacement in PAHCM group [(10.16±1.17) mm vs(8.42±1.28) mm,(10.25±1.07) mm vs(8.36±1.20) mm,(10.54±1.01) mm vs(8.84±1.08) mm,(9.95±0.83) mm vs(8.58±1.09) mm,(9.86±0.39) mm vs(8.50±0.46) mm, t= 5.10, 6.00, 5.87, 5.11, 11.48, P〈0.05], and the difference at SD of lateral and inferior wall was not statistically significant [(9.03±1.35) mm vs(8.30±1.27) mm,(9.25±1.13) mm vs(8.52±1.21) mm, t=2.25, 2.27, P〈0.05]. Compared with the control group, the dif
出处 《中华医学超声杂志(电子版)》 CSCD 2015年第10期786-791,共6页 Chinese Journal of Medical Ultrasound(Electronic Edition)
基金 辽宁省科技厅科学技术计划项目(2013225049)
关键词 超声心动图 心尖肥厚型心肌病 二尖瓣环位移 心室 收缩功能 Echocardiography Pre-apical hypertrophic cardiomyopathy Mitral annular displacement Ventricle Left Systolic function
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参考文献12

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