摘要
目的分析32例肥厚型心肌病伴心房颤动患者的临床特点。方法选择1994-2005年在解放军总医院心脏中心就诊的肥厚型心肌病患者158例,平均随访(4.2±2.8)年,按病史、心电图、动态心电图是否记录到心房颤动分为房颤组和非房颤组,观察并比较2组患者的临床特点。结果(1)肥厚型心肌病伴房颤患者共32例,占全部肥厚型心肌病患者的20.3%,其中阵发性房颤14例(43.7%),持续性房颤18例(57.3%),无症状性房颤5例(15.6%);(2)与非房颤组患者比较,房颤组患者平均年龄偏大(58±10.4vs46±12.6)岁(P<0.01),左房直径大(42±3.5vs34±5.3)mm(P<0.01);(3)房颤组12例(心力衰竭8例,猝死4例)发生心血管事件,非房颤组9例(心力衰竭6例,猝死3例)发生心血管事件。房颤组患者中,房颤引发室颤1例(3%),脑栓塞2例(6.3%),下肢动脉栓塞2例(6.3%)。结论(1)20.3%肥厚型心肌病患者伴心房颤动,其中43.7%为阵发性房颤,57.3%为持续性房颤,15.6%为无症状性房颤;(2)与肥厚型心肌病不伴房颤患者相比,伴房颤患者年龄偏大,心血管事件发生率高。
Objective To analyze the clinical characteristics of 32 cases of hypertrophic cardiomyopathy with atrial fibrillation（AF）. Methods A total of 158 hypertrophic cardiomyopathy cases （1994-2005） followed up for 4.2±2.8 years were collected from this hospital. The patients were divided into 2 groups, one group included patients with AF, and the other group consisted of patients without AF. Results （1）Thirty-two cases（20. 3%） had atrial fibrillation. Of them, 14 （43.7%） had paroxysmal AF and 5 （15.6%） had AF without related symptom. （2）AF patients were relatively older than those without AF, and had greater diameter of left atrium. （3）Twelve AF patients had cardiovascular events （8 heart failure and 4 sudden death, of which one was caused by atrial fibrillation-induced ventricular fibrillation） and 9 patients without AF had cardiovascular events（6 heart failure and 3 sudden death）. Of the patients with AF, 2 had cerebral embolism, and 2 had lower extremity arterial embolism. Conclusion （1）Twenty-one percent of the hypertrophic cardiomyopathy patients had atrial fibrillation. Of them, 43.7% had paroxysmal AF and 15.6 % had AF without related symptom. （2）The average age of the patients with AF was higher than that of those without AF and the incidence of cardiovascular events was higher in patients with AF than in those without AF.
出处
《中华老年多器官疾病杂志》
2007年第2期117-118,129,共3页
Chinese Journal of Multiple Organ Diseases in the Elderly
关键词
心肌病
肥大性
心房颤动
cardiomyopathy, hypertrophic
atrial fibrillation
