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手法复位联合凉血散瘀汤内服外洗治疗嵌顿痔的多中心随机对照临床研究 被引量:5

Treatment of incarcerated hemorrhoids by manual reduction combined “Lingxue Sanyu Decoction”orally and sitz bath:a multicenter clinical study
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摘要 目的观察手法复位联合凉血散瘀汤内服外洗治疗嵌顿痔的临床疗效。方法将120例嵌顿痔患者随机分为联合组、对照1组与对照2组,每组40例。联合组采用手法复位联合凉血散瘀汤内服外洗治疗,对照1组采用手法复位联合凉血散瘀汤内服治疗,对照2组采用手法复位联合凉血散瘀汤外洗治疗。各组疗程均为1周,观察临床疗效,比较各症状体征评分的变化情况,并评价疗法安全性。结果 1最终完成试验者110例,联合组37例,对照1组37例,对照2组36例。2联合组、对照1组与对照2组临床总有效率分别为100.00%、83.78%和88.89%。联合组分别与对照1组、对照2组临床疗效比较,差异有统计学意义(P<0.05);对照1组与对照2组比较,差异无统计学意义(P>0.05)。3组间治疗后比较,联合组各症状体征评分均显著低于对照1组与对照2组(P<0.05)。4各组不良反应发生率比较,差异无统计学意义(P>0.05)。结论手法复位联合凉血散瘀汤内服外洗治疗嵌顿痔的疗效满意。 Objective To observe the clinical effect of manual reduction combined "Lingxue Sanyu Decoction" orally and sitz bath in the treatment of incarcerated hemorrhoids. Methods 120 patients with incarcerated hemorrhoid were randomly divided into three groups: combination group, control group 1 and control group 2, 40 cases in each group. The combination group were treated by manual reduction combined " Lingxue Sanyu Decoction " orally and sitz bath, control group 1 were treated by manual reduction combined " Lingxue Sanyu Decoction " orally, control group 2 were treated by manual reduction combined "Lingxue Sanyu Decoction " sitz bath. The treatment course of each group was 1 week. The clinical effect and the changes of primary clinical symptoms in all cases were observed and given safety evaluation after treatment. Results ①The final subjects was 110 patients, combination group of 37 cases, control group 1 of 37 cases, and control group 2 of 36 cases. ②The total effective rates was 100.00% in combination group, 83.78% in control group 1 and 88.89% in control group 2. Clinical curative effect comparison between combination group and control group 1, combination group and control group 2, the difference was statistically significant( P 〈 0.05 ) , while there was no statistically significant difference between control group 1 compared with control group 2 (P 〉 0.05 ). ③After the treatment, the symptoms and signs scores were significantly lower in the combination group than that of control group 1 and control group 2 ( P 〈 0.05 ). ④The incidence of adverse reactions of each group, there was no statistically significant difference between all the groups ( P 〉 0.05 ). Conclusion Manual reduction combined "Lingxue Sanyu Decoction" orally and sitz bath for treatment of Incarcerated hemorrhoids was an effective therapy with TCM characteristics.
出处 《上海中医药杂志》 2015年第11期57-61,共5页 Shanghai Journal of Traditional Chinese Medicine
基金 上海市卫生局"杏林新星计划"项目(ZYSNXD011-RC-XLXX-20130030) 上海市科委浦东新区科技发展基金项目(PKJ2012-Y32) 上海市浦东新区卫生局传统型中医临床示范学科建设项目(PDZYXK-T-2012008)
关键词 嵌顿痔 联合疗法 手法复位 凉血散瘀汤 内服 外洗 incarcerated hemorrhoids combination therapy manual reduction "Lingxue Sanyu Decoction" orally sitz bath
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