摘要
目的研究分析不同时机将犬牙移入牵张成骨区后龈沟液的天门冬氨酸氨基转移酶(AST)水平变化。方法 8只无牙周疾病且正常恒牙列beagle犬行牵张成骨术后分为两组(2周和6周),均行牙齿移入牵张成骨新骨区。观察对实验牙加力1、2、3、7、14、28d后龈沟液中AST水平变化。结果两组实验牙龈沟液AST水平前3d均存在上升趋势,且2周组上升较6周组明显;7d后AST水平呈现下降趋势,在21d达最低,并逐渐恢复;当28d时AST水平再次上升。结论牵张成骨2周后实验牙移入新骨区龈沟液AST整体水平较6周后明显升高,但随着时间的推移AST水平改变并非呈线性升高。
Objective To observe the dynamic changes of aspartate transaminase（AST）in gingival crevicular fluid on tooth movement in new bone area after distraction osteogenesis at different time.Methods The distraction osteogenesis surgical procedure was performed in 8beagle dogs without periodontal disease and normal teeth,experimental teeth were transplanted into the bone regeneration area after 2weeks and after 6weeks.Comparative analysis AST of each time（1,2,3,7,14,28 dafter distraction）dynamic changes in gingival crevicular fluid.Results The AST level of gingival crevicular fluid in experimental tooth was rising for the first three days,and the group of two weeks were significantly higher than 6weeks;AST levels after 7dshowed a trend of decline,down to the lowest point at 21 d,and gradually restored,AST levels reached a higher level again in the 28 d.Conclusion The AST level of experimental teeth increased significantly after 2weeks than after 6weeks,but over time the AST level change is not linear,this change has certain guiding significance for the clinical research in the future.
出处
《重庆医学》
CAS
北大核心
2015年第32期4478-4480,共3页
Chongqing medicine
基金
安徽省科技厅重点课题(05023084)
安徽省教育厅省级重点课题(KJ2008A160)
关键词
尖牙
天冬氨酸氨基转移酶类
牵张成骨
龈沟液
cuspid
aspartate aminotransferases
distraction osteogenesis
gingival crevicular fluid
