摘要
引言癌症的发病率逐年增加,据估算到2020年,我国每年的发病人数将达到1500万。骨骼是转移瘤的第三大好发部位,仅次于肺和肝脏。最易发生骨转移的原发肿瘤有乳腺癌、前列腺癌和肺癌。这些肿瘤不但有明显的骨转移倾向,而且发病率高[1]。骨转移中以脊柱转移最为常见。脊柱转移瘤70%发生在胸段,20%发生在腰段,10%发生在颈段。椎体是脊椎转移瘤最常受累的部位（60%~70%）,其次是椎板和椎弓根。
With longer survival time of cancer patients, spine metastasis is of growing importance. Management of spine metastasis is quite complicated. Advances in research, surgical techniques and radiosurgical implementation have altered drastically the treatment paradigm for spine metastasis. At present, multi-disciplinary therapy including orthopedics, oncology, radiation oncology, neurosurgery and other disciplines are recommended. Radiation therapy has been proven effective to relieve the pain of spinal metastases. In patients with severe spinal metastases, who is unfavorable for operation, radiotherapy is preferred. Radiation therapy can be used alone or combined with chemotherapy and surgery. Stereotactic radiotherapy makes up for the deficiency of the traditional radiation therapy, giving maximum radiation dose to tumors on the premise of suitable surrounding organ tolerance. Traditional external radiation therapy, brachytherapy, intensity-modulated radiotherapy, stereotactic radiotherapy are commonly used. Radiation therapy of spinal metastases will be reviewed in this paper.
出处
《中国骨与关节杂志》
CAS
2015年第10期802-805,共4页
Chinese Journal of Bone and Joint
基金
北京市科委首都临床特色课题<脊柱转移瘤硬膜外脊髓压迫症减压手术的预后因素分析>(z131107002213052)
