摘要
卵磷脂-胆固醇酰基转移酶(lecithin - cholesterolacyltransferase, LCAT)缺乏肾病为临床罕见病,临床表现为蛋白尿及肾功能减退,容易误诊为原发性肾小球肾炎,现将1例卵磷脂.胆固醇酰基转移酶缺乏相关肾病病例汇报如下,通过文献复习,旨在提高对该病认识。
出处
《中华肾脏病杂志》
CAS
CSCD
北大核心
2015年第10期790-792,共3页
Chinese Journal of Nephrology
参考文献12
-
1Qu Sl, Fan HZ, Blanco - Vaca F, et al. In vitro expression of natural mutants of human lecithin:cholesterol acyltransferase[l]. 1 Lipid Res, 1995,36(5): 967-974. 被引量:1
-
2Funke H, von Eckardstein A, Pritchard PH, et al. Genetic and phenotypic heterogeneity in familial lecithin: cholesterol acyltransferase (LCAT) deficiency. Six newly identified defective alleles further contribute to the structural heterogeneity in this disease[J]. J Clin Invest, 1993,91(2): 677-683. 被引量:1
-
3Idzior- Walus B. Familial LCAT deficiency[l]. Przegl Lek, 2001, 58(10): 919-923. 被引量:1
-
4Scarpioni R, Paties C, Bergonzi G. Dramatic atherosclerotic vascular burden in a patient with familial lecithin - cholesterol acyltransferase (LCAT) deficiency [J]. Nephrol Dial Transplant, 2008, 23(3): 1074-1075 . 被引量:1
-
51ahanzad I, Amoueian S, Attaranzadeh A. Familial lecithincholesterol acyltransferase deficiency[J]. Arch Iran Med, 2009,12 (2): 179-181. 被引量:1
-
6Lager DJ, Rosenberg BF, Shapiro H, et al. Lecithin cholesterol acyltransferase deficiency: ultrastructural examination of sequential renal biopsies[J]. Mod Pathol, 1991,4(3): 331-335. 被引量:1
-
7Takahashi S, Hiromura K, Tsukida M, et al. Nephrotic syndrome caused by immune - mediated acquired LCAT deficieney[l]. 1 Am Soc Nephrol, 2013, 24(8): 1305-1312. 被引量:1
-
8Strem EH, Sund S, Reier-Nilsen M, et al. Lecithin: Cholesterol Acyltransferase (LeA T) Deficiency: renal lesions with early graft recurrence[J]. Ultrastruct Pathol, 2011, 35(3): 139-145. 被引量:1
-
9Stockenbroek RM, van den Bergh Weerman MA, Hovingh GK, et al. Familial LCAT deficiency: from renal replacement to enzyme replacement [J]. Neth J Med, 2013, 71(1): 29-31. 被引量:1
-
10张庭廷,夏晓凯.卵磷脂胆固醇酰基转移酶缺乏综合征[J].生命的化学,1999,19(6):294-296. 被引量:4
二级参考文献34
-
1张小瑛,崔若兰,李霖,李闻捷.改良的LCAT测定及其在肾脏疾病中的临床意义[J].肾脏病与透析肾移植杂志,1995,4(4):318-319. 被引量:4
-
2Jahanzad I,Amoueian S,Attaranzadeh A.Familial lecithin-cholesterol acyltransferase deficiency[J].Arch Iran Med,2009,12(2):179-81. 被引量:1
-
3Idzior-Walu B,Sieradzki J,Rostworowski W,et al.Familial LCAT deficiency-clinical picture[J].Pol Arch Med Wewn,2000,104 (3):591-6. 被引量:1
-
4Scarpioni R,Paties C,Bergonzi G.Dramatic atherosclerotic vascular burden in a patient with familial lecithin-cholesterol acyltransferase (LCAT) deficiency[J].Nephrol Dial Transplant.2008,23(3):1074-5. 被引量:1
-
5Li Min,Biochem Biophys Acta,1998年,1391卷,2期,256页 被引量:1
-
6Kuivenhoven JA, Pritchard H, Hill J, et al.The molecular pathology of lecithin : cholesterol acyhransferase ( LCAT ) deficiency syndromes. J Lipid Res, 1997,38 (2) : 191-205. 被引量:1
-
7Shoji K, Morita H, Ishigaki Y, et al. Lecithin-cholesterol acyltransferase (LCAT) deficiency without mutations in the coding sequence : a case report and literature review. Clin Nephrol, 2011,76 (4) :323-328. 被引量:1
-
8Li M, Kuivenhoven JA, Ayyobi AF, et al. T→ G or T→A mutation introduced in the branchpoint consensus sequence of intron 4 of lecithin : cholesterol aeyltransferase ( LCAT ) gene : intron retention causing LCAT deficiency. Biochim Biophys Acta, 1998, 1391 (2) :256-264. 被引量:1
-
9Frase~t GM,Soverini L, Tampieri E, et al.A 33-year-old man with nephrotie syndrome and lecithin-cholesterol aeyltransferase (LCAT) deficiency. Description of two new mutations in the LCAT gene. Nephrol Dial Transplant,2004,19(6) : 1622-1624. 被引量:1
-
10Gjone E, Blomhoff JP, Skarbovik AJ. Possible association between an abnormal low density lipoprotein and nephropathy in lecithin: cholesterol aeyltransferase deficieney.Cliniea Chimica Aeta, 1974,54 (1) :11-8. 被引量:1
共引文献4
-
1吕俊华,程朝晖,张世平,钟玲.红丝线草提取物对高血压并发高脂血症模型大鼠调脂作用的研究[J].陕西医学杂志,2005,34(4):396-399. 被引量:10
-
2谢运昌,蒋小华,张冕.红丝线挥发油的化学成分[J].广西植物,2008,28(1):136-138. 被引量:9
-
3徐玉琳,林颖,周诚,黄恩,何茵茵.UV法测定狗肝菜与红丝线草的多糖含量[J].中药新药与临床药理,2008,19(5):387-389. 被引量:10
-
4钟永忠,朱莹,曾彩虹.Ⅲ型高脂蛋白血症肾脏损害的临床病理特征——附3例报告并文献复习[J].肾脏病与透析肾移植杂志,2019,28(5):418-422.
同被引文献8
-
1罗盈,刘煜,肖力,唐丹,刘伏友,孙林.异位脂肪沉积与糖尿病肾病肾损伤的研究进展[J].中华肾脏病杂志,2016,32(1):71-76. 被引量:10
-
2Tianhua Xu,Zitong Sheng,Li Yao.Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment[J].Frontiers of Medicine,2017,11(3):340-348. 被引量:26
-
3阮雄中.“脂质肾毒性学说”的最新研究进展[J].中国科学:生命科学,2018,48(1):47-55. 被引量:10
-
4杨简,杨英杰,杨倩,丁国华.ABCA1在血管紧张素Ⅱ诱导足细胞胆固醇蓄积中的作用[J].中华肾脏病杂志,2018,34(2):115-121. 被引量:2
-
5周翠,杨倩,杨英杰,胡继佳,梁伟,丁国华.自噬在高糖诱导的足细胞脂质蓄积中的作用[J].中华肾脏病杂志,2018,34(10):765-770. 被引量:5
-
6宗慧敏,王霞,刘春蓓,周敏林,梁少姗,章海涛,刘志红.肥胖相关性肾病代谢指标的特点[J].肾脏病与透析肾移植杂志,2018,27(5):401-406. 被引量:7
-
7王冲,王贵松,李月红.异常高密度脂蛋白在慢性肾脏病中的研究进展[J].中华肾脏病杂志,2019,35(4):316-320. 被引量:6
-
8Jian Xiao,Jie Luo,Ao Hu,Ting Xiao,Meixin Li,Zekai Kong,Luyi Jiang,Zimu Zhou,Yacheng Liao,Chang Xie,Beibei Chu,Honghua Miao,Boliang Li,Xiongjie Shi,Bao-Liang Song.Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins[J].Science China(Life Sciences),2019,62(9):1117-1135. 被引量:8
二级引证文献2
-
1张国娟,王宏娟,徐世明,梁巧静.高糖培养对大鼠肾小球系膜细胞内胆固醇含量的影响[J].中国医师杂志,2023,25(2):242-246.
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2吴爱君,程冉,曾艳秋,黎创,黄丽华,王晓婉,胡天祥,陆智昇,黄清明,毛炜,徐鹏,田瑞敏.基于脂质肾毒性学说探析慢性肾脏病“湿邪内蕴”的现代生物学机制及“从湿论治”的潜在靶点[J].中国中医基础医学杂志,2024,30(2):269-274. 被引量:3
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1路辉,王炎焱,陈馥,吴英.脑梗塞患者60例血浆卵磷脂-胆固醇酰基转移酶活性变化及临床意义[J].沈阳部队医药,2002,15(2):155-156. 被引量:1
-
2路辉,王炎焱,王殿侠,陈馥,吴英.脑梗塞患者血浆LCAT活性的动态研究[J].武警医学,2001,12(7):422-423.
-
3曲东锋.肾功能减退预示着急性卒中后死亡的危险更高[J].国外医学(脑血管疾病分册),2002,10(4):286-286.
-
4丁素菊,毕晓莹,邓本强,张永巍.血脂康对高脂血症合并脑梗死患者血脂及LCAT活性的影响[J].中国微循环,2006,10(3):208-209. 被引量:6
-
5路辉,王炎焱,陈馥,吴英.脑梗塞患者60例动态观察血浆LCAT活性及其临床意义[J].解放军保健医学杂志,2000,2(3):41-42.
-
6李睿,杨文明,李祥.肝豆状核变性致糖尿病2例[J].中医药临床杂志,2014,26(11):1191-1192.
-
7初开秋,唐晓燕,董争鸣.血浆卵磷脂-胆固醇酰基转移酶与红细胞膜脂质成分的相关性探讨[J].现代检验医学杂志,2004,19(6):13-14. 被引量:1
-
8潘文君,李海英,黄丽萍.脑出血血肿清除术后并发急性肾功能衰竭1例报告[J].西藏科技,1997(2):65-65.
-
9陈丹,左红霞,黄建新,史科其,黄立华.急性缺血性脑卒中患者肾功能状况及其相关因素的研究[J].中国现代医生,2013,51(12):36-38. 被引量:1
-
10赵仁亮,王春霞,牟晓峰,唐盛孟.脑梗塞病人血浆LCAT活性与脂蛋白及红细胞膜脂质含量的关系[J].齐鲁医学杂志,1998,13(1):18-20.