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含诺华敏的脱敏剂与氟化物涂膜联合堵塞牙本质小管的体外研究 被引量:10

Occluding effects of desensitizer containing Nova Min combined with fluor protector on dentinal tubules:an invitro study
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摘要 目的 :观察含诺华敏的脱敏剂与氟化物涂膜联合应用对牙本质小管的堵塞作用及抗酸、抗洗刷能力,以期为牙本质过敏症的临床治疗提供理论依据。方法:选择因正畸需要拔除的完整无龋坏的前磨牙30颗,制备成2 mm厚的牙本质薄片后,一分为4,形成120个过敏模型,随机分为4组(n=30),分别用蒸馏水(A组)、氟化物涂膜(B组)、奥敏清(C组)、氟化物涂膜和奥敏清联合(D组)处理样本,置于人工唾液中24 h,每组再随机分成3个亚组,分别接受直接观察、酸蚀及刷牙处理,分析牙本质小管的堵塞率。采用SPSS 13.0软件包对数据进行统计学分析。结果:A组牙本质小管完全开放,B、C、D组均表现出良好的封闭性,其中D组效果最佳,与其他3组差异显著,且抗酸性和抗洗刷能力更强(P<0.01)。结论:含诺华敏的脱敏剂与氟化物涂膜联合应用堵塞牙本质小管的效果最佳,且具有较好的抗酸性和抗洗刷性能。 PUPPOSE: To observe the occlusion effect, acid resistance and abrasion resistance of desensitizer containing NovaMin combined with fluor protector on dentin tubules, in order to provide theoretical basis for clinical treatment of dentin hypersensitivity. METHODS: Thirty extracted intact and non-carious human premolars for orthodontic treatment were selected and made into 2 mm thick dentin slices. Each slice was cut into 4 parts to form 120 sensitive dentin models and randomly divided into 4 groups (n=30). Distilled water (group A), fluor protector (group B), Ominq desensitizer (group C) and fluor protector combined with Ominq desensitizer (group D)were applied respectively on the exposed dentin surfaces. After immersed in the artificial saliva for 24 h, each group was divided into 3 subgroups randomly to undergo direct observation, acid corrosion and tooth brushing test, then the plugging rate of dentin tubules was statistically analyzed with SPSS 13.0 software package. RESULTS: Dentin tubules in group A were completely open, while good occluding effects were found in group B, C and D. Among them, group D displayed the best occlusion effect, and ability of acid and abrasion resistance compared with other 3 groups (P〈O.01). CONCLUSIONS: Treatment with desensitizer containing NovaMin combined with fluor protector shows better occluding effects in the dentin tubules and better ability of acid and abrasion resistance.
出处 《上海口腔医学》 CAS CSCD 2015年第5期535-540,共6页 Shanghai Journal of Stomatology
基金 辽宁省医学高峰建设工程重点科研项目(200909)~~
关键词 牙本质过敏症 脱敏剂 牙本质小管 Dentin hypersensitivity Desensitizer Dentin tubules
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