摘要
目的 :探讨哮喘患儿的血清LPC和Apo B水平及其临床意义。方法 :选取我院收治的36例哮喘患儿为观察组,同期42例健康患儿为对照组,比较两组血清LPC和Apo B水平。结果 :观察组不同时期Apo B水平比较差异具有统计学意义(P<0.05);观察组急性发作期Apo B水平明显高于对照组(P<0.05);观察组LPC 18∶2和LPC20∶5水平均明显高于对照组(P<0.05);观察组急性发作期LPC 20∶5水平明显高于缓解期(P<0.05)。结论 :LPC及Apo B是哮喘患儿发病过程中的重要调节因子,在发病机制中均有重要作用。
Objective： To investigate the changes of serum lysophosphatidylcholine（LPC） and apolipoprotein B（Apo B） in children with asthma and their clinical significance. Methods： Thirty-six cases of children with asthma in our hospital were selected as an observation group and 42 cases of healthy children in the same period as a control group. The levels of serum LPC and Apo B were compared between two groups. Results： The comparison of Apo B levels in different periods in the observation group showed statistical significance（P0.05）. The Apo B level in acute exacerbation period and the LPC 18：2 and LPC 20：5 level were significantly higher in the observation group than in the control group（P0.05）. The LPC 20：5 level in the observation group was significantly higher in acute exacerbation period than in the remission period（P0.05）. Conclusion： LPC and Apo B levels are the important regulators in the pathogenesis of asthma, which play important roles in the pathogenesis.
出处
《上海医药》
CAS
2015年第19期48-49,70,共3页
Shanghai Medical & Pharmaceutical Journal
基金
江西省卫生厅2013年度科技计划项目(项目编号:20133212)
