摘要
目的对桑杏汤（散）及其加减方在治疗呼吸系统疾病进行了系统评价,将重要依据提供了桑杏汤及其加减方在呼吸系统疾病中的应用。方法对研究的文献中桑杏汤及其加减方治疗呼吸系统疾病应用随机对照试验,并进行了相应的Meta分析。结果 1310名受试者中有12个随机对照试验,其中只有对Jadad的评分为1个2分,除此之外全为1分,所以都为质量较低的C级研究。OR=4.89,95%CI[2.73~8.38]为桑杏汤及其加减方对肺部疾病的治疗和西药对比合并的总体效果;OR=4.58,95%CI[2.71~7.70]为桑杏汤及其加减方在加上西药对肺部疾病治疗与西药对比的合并总体治疗效果;O R=4.52,95%CI[1.83~10.92]为桑杏汤及其加减方对支气管炎的治疗和西药对比合并的总体效果;OR=6.96,95%CI[2.39~20.73]为桑杏汤及其加减方对咳嗽引起的哮喘治疗和西药对比合并的总体效果;OR=8.95,95%CI[4.15~19.14]为桑杏汤及其加减方（加西药）对肺炎的治疗和西药对比合并的总体效果;将纳入的研究中超出3个进行漏斗分析,其中存在着发表表偏倚。结论当前对桑杏汤及其加减方在治疗呼吸系统疾病方面进行临床研究,发现有优势存在,其中对咳嗽、咳嗽导致的哮喘、肺炎等都是治疗的范围,报道没有不良的反应,可是研究的数量不广泛,使这次的研究效果受到影响。
Objective To make systematic evaluation of modified Sangxing decoction（powder） in the treatment of respiratory diseases,and provide important basis in the application of respiratory system disease. Methods Literatures related to respiratory diseases were treated with Sangxing decoction studied by randomized controlled trials, and the corresponding Meta analysis were evaluated. Results There were 12 randomized controlled trials in 1310 subjects, of which the Jadad score was 1 points in addition to one 2 points, so for the studies were the low quality grade C. OR = 4.89, 95% CI [2.73 ~ 8.38] Sangxing decoction and its modified decoction in the treatment of lung disease and compared to the general effect of the combined Western medicine. OR = 4.58, 95 % CI [2.71 to 7.70] for Sangxing decoction and its modified decoction combined with Western medicine in the treatment of lung disease compared with Western medicine was the merger overall treatment effect; OR = 4.52, 95% CI [1.83 ~ 10.92] Sangxing decoction and its modified decoction in the treat-ment of bronchitis and compared to the general effect of the combined Western medicine; OR = 6.96, 95 % CI [2.39 ~ 20.73] Sangxing decoction and its modified decoction in the treatment of cough caused by asthma therapy and Western medicine compared to the general effect of the merger; OR = 8.95, 95% CI [8.95 to 19.14] for Sangxing decoction and its modified decoction（add Western medicine） in the treatment of pneumonia and contrast the general effect of the combined Western medicine. The inclusion of the study is more than 3out of the funnel analysis, which has a publication bias. Conclusion At present, the clinical research of Sangxing decoction and its modi-fied decoction in the treatment of respiratory diseases were carried out. We found that there were advantages, including cough, asthma in-duced by cough and pulmonary disease. There were no adverse reactions, but the number of studies were not widespread, so that the effect of the study was affected.
出处
《中国中医药现代远程教育》
2015年第18期43-44,共2页
Chinese Medicine Modern Distance Education of China
关键词
桑杏汤
呼吸系统疾病
系统评价
肺病
Sangxing decoction
respiratory system diseases
system evaluation
pulmonary disease
