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儿童社区获得性肺炎的临床特点和治疗 被引量:3

Clinical characteristics and treatment of children community-acquired pneumonia
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摘要 目的探讨儿童社区获得性肺炎的临床特点和治疗预后。方法儿童社区获得性肺炎480例采用抽签成组方法分为治疗组与对照组,各240例,对照组给予头孢曲松钠治疗,治疗组在此基础上加用炎琥宁注射液进行治疗,比较两组的治疗效果。结果治疗组的总有效率为96.7%,对照组总有效率为89.2%,两组比较差异具有统计学意义(P<0.05)。治疗组的咳嗽、啰音、发热消失时间都明显少于对照组,对比差异有统计学意义(P<0.05)。两组治疗前血浆C-反应蛋白(CRP)与白介素(IL-6)值对比,差异无统计学意义(P>0.05),治疗后上述值在组内与组间对比差异均有统计学意义(P<0.05)。结论儿童社区获得性肺炎采用炎琥宁注射液结合抗生素进行治疗能有效提高疗效,缓解临床症状,其作用与降低血浆CRP与IL-6水平有明显相关性。 Objective To investigate the clinical characteristics and treatment prognosis of children community-acquired pneumonia. Methods A total of 480 children with community-acquired pneumonia were divided into treatment group and control group by draw lots, and each group contained 240 cases. The control group received ceftriaxone sodium for treatment, while the treatment group was treated by additional andrographolide injection. Curative effects of the two groups were compared. Results The total effective rate of the treatment group was 96.7%, and that of the control group was 89.2%. The difference between the two groups had statistical significance(P〈0.05). The treatment group had less cough, rales, fever, and disappearance time than the control group, and the difference was statistically significant(P〈0.05). The difference of plasma C-reactive protein(CRP) and interleukin-6(IL-6) value was no obvious between the two groups before treatment(P〉0.05). After treatment, these indexes had statistically significant difference both in the groups and between the groups(P〈0.05). Conclusion Andrographolide injection combined with antibiotic in the treatment of children community-acquired pneumonia can effectively improve curative effect and relieve clinical symptoms. There is an obvious correlation between its effect and reducing level of plasma CRP and IL-6.
出处 《中国实用医药》 2015年第5期17-19,共3页 China Practical Medicine
关键词 儿童 社区获得性肺炎 炎琥宁注射液 头孢曲松钠 炎症因子 Children Community-acquired pneumonia Andrographolide injection Ceftriaxone sodium Inflammatory factor
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