摘要
目的探讨儿童肺炎支原体感染进行布地奈德与阿奇霉素联合治疗的临床效果。方法选取我院2013年4月~2014年3月的94例肺炎支原体感染患儿,按照随机数字表法分为研究组和对照组,每组47例。两组均行常规治疗,对照组在常规治疗基础上行阿奇霉素治疗,研究组在对照组基础上行布地奈德雾化吸入治疗。治疗3周后,对比两组临床效果以及不良反应状况。结果研究组的临床总有效率为87.2%,显著高于对照组66.0%,差异有统计学意义（P〈0.05）;研究组的X线平片、啰音、咳嗽、喘息等恢复情况显著优于对照组（P〈0.05）;研究组用药后不良反应发生率为14.9%,对照组为8.5%,两组差异无统计学意义（P〉0.05）。结论儿童支原体肺炎应用布地奈德联合阿奇霉素治疗,可缩短其治疗时间,且安全有效,可促进患儿的病情康复,值得临床推广。
Objective To clinical effect of Budesonide combined with Azithromycin for children with Mycoplasma pneumonia infection. Methods 94 children with Mycoplasma pneumonia infection treated in our hospital from April 2013 to March 2014 were selected.They were randomly divided into research group and control group according to the random number table method,47 cases in each group.Two groups were given conventional treatment,the control group was adopted azithromycin on the basis of conventional treatment,research group was adopted azithromycin on the basis of control group. After 3weeks of treatment,the clinical effect,remission of clinical symptoms and adverse reactions in two groups were compared. Results The effective rate of research group was 87.2%,which was significantly higher than66.0% of control group（P0.05）.The recovery of breathing, coughing,rale,X-ray plain of research group was significantly better than those of control group（P0.05）.The adverse event rate of research group and control group was 14.9% and8.5%,the difference was not statistically significant between two groups（P 0.05）. Conclusion For children with Mycoplasma pneumonia infection,budesonide combined with azithromycin has an obvious clinical effect,can shorten the treatment time and promote the patient′s disease rehabilitation,and is safe and effective.which is worthy of clinical promotion.
出处
《中国当代医药》
2015年第28期130-132,共3页
China Modern Medicine
关键词
儿童支原体肺炎
阿奇霉素
布地奈德
临床效果
Children Mycoplasma pneumonia
Azithromycin
Budesonide
Clinical effect
