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低钙透析液联合碳酸镧对血液透析患者钙磷代谢的影响 被引量:2

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摘要 目的 :研究应用低钙透析液联合碳酸镧对维持性血液透析(MHD)患者钙磷代谢及全段甲状旁腺激素(i PTH)的影响。方法:选取长期使用1.5mmol/L浓度钙透析液,同时伴有血i PTH<300pg/m L及血磷、血钙水平升高患者31例,观察其在改用1.25mmol/L浓度钙透析液及碳酸镧治疗1个月(T1)、2个月(T2)、3个月(T3)后血钙、血磷及血i PTH水平的变化。结果:血清钙较治疗前明显下降,而且呈继续下降趋势,T1、T2、T3分别为2.59±0.10 mmol/L、2.50±0.11 mmol/L、2.34±0.13 mmol/L,差异有统计学意义(均P<0.05)。治疗前血磷为2.56±0.26mmol/L,T1、T2、T3分别为2.09±0.31 mmol/L、1.82±0.26 mmol/L,1.88±0.26 mmol/L,血磷水平较治疗前明显下降,差异均有统计学意义(均P<0.05),治疗前血i PTH为135.02±80.36pg/m L,T3时升高为206.58±91.83 pg/m L,较治疗前明显下降,差异有统计学意义(P<0.05)。应用低钙透析液及碳酸镧治疗后血钙、血磷及钙磷乘积有显著下降,差异有统计学意义(P<0.05)。结论:低钙透析液联合碳酸镧能有效地纠正高钙、高磷血症,控制钙磷乘积,上升PTH水平,可能起到防止低转运骨病的作用。
出处 《交通医学》 2015年第4期363-365,共3页 Medical Journal of Communications
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参考文献11

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