摘要
目的 探讨动态增强MRI扫描评估甲氨蝶呤（MTX）阻断治疗早期未分化关节炎中的价值。方法 对15例患者采用动态MRI增强扫描进行随访,动态观察患者腕关节滑膜的改变,结合其他检查进行评分并评估MTX阻断治疗的价值。结果 15例患者均进行了MRI检查,所有病例均进行了随访,对15例怀疑有滑膜改变的患者进行了增强检查,滑膜轻度增厚12例,3例未见明显强化,随访6~24个月后,2例患者转为RA。结论 MRI增强扫描在动态随访观察MTX阻断治疗早期类风湿性关节炎中具有较好的价值。
Objective To explore the value of dynamic contrast-enhanced MRI scan in the evaluation of MTX （metho trexate） blockade therapy for undifferentiated arthritis. Methods ACR/EULAR score less than 6 of the 15 patients were done with wrist MR imaging, and dynamic follow-up observed of changes in synoviun. We analysed the correlation of wrist synovial MRI score with early rheumatoid arthritis. Results All the 15 patients were detected by MRI and underwent follow-up. 12 patients with synovial changes were checked by enhanced MRI, including 10 cases with the synovial mild thickening and two cases with no significant strengthening. Conclusion Enhanced MRI has good value in a dynamic follow-up observation of early rheumatoid arthritis and provides a theoretical basis for early clinical intervention.
出处
《医学影像学杂志》
2015年第10期1868-1870,共3页
Journal of Medical Imaging
基金
浙江中医药管理局课题(项目编号:2001ZA041)
关键词
类风湿关节炎
腕关节
磁共振成像
滑膜炎
Rheumatoid arthritis
Wrist
Magnetic resonance imaging
Synovitis
