摘要
目的研究恶性肿瘤患者的血栓弹力图临床检测价值。方法应用血栓弹力图仪进行R值、K值、Ma值与Mε值检测;应用凝固法进行APTT、TT、PT检测;应用双缩脲法进行Fg检测。结果恶性肿瘤组血栓弹力图的R值与K值明显缩短、Mε与Ma值明显增宽,与正常对照组比较差异具有统计学意义(P<0.001);恶性肿瘤组APTT、TT、PT、Fg值与正常对照组比较差异无统计学意义(P>0.05)。结论应用血栓弹力图动态观察恶性肿瘤患者凝血状态比传统的凝血相关指标敏感,对指导部分恶性肿瘤治疗具有一定的临床意义。
Objective To study the clinical value of thrombelastograph in patients with malignant tumors. Methods The R,K, Ma and Mε values were detected by thrombelastograph; the APTT, TT, PT values were tested by the coagulation method ;and Fg was examined by application the biuret method. Results The R and K values of TEG in malignant group were significantly shorter compared with the normal group. In addition, the Me and Ma values in malignant group were widened compared with the normal group （P〉0. 001）. The APTT, TT, PT and Fg values in malignant group showed no significant differences compared with the normal group （P〉0. 05）. Conclusion Dynamic observation of the thrombelastograph of patients with malignant tumor is sensitive to the traditional coagulation, and may have some clinical value in the treatment of malignant tumor.
出处
《临床输血与检验》
CAS
2015年第5期407-409,共3页
Journal of Clinical Transfusion and Laboratory Medicine
关键词
恶性肿瘤
血栓弹力图
高凝状态
Malignant tumor Thrombelastograph Hypereoagulation
