摘要
目的：探讨经导管动脉化疗栓塞（transcatheter arterial chemoembolization，TACE）联合 CT 引导下水循环冷却式射频消融（radiofrequency ablation，RFA）治疗原发性肝癌的临床疗效。方法2011年10月～2014年8月对32例原发性肝癌41个病灶（直径＜3．0 cm 病灶7个，3．0～4．0 cm 6个，＞4．0～5．0 cm 9个，＞5．0 cm 19个）采用 TACE 联合 CT 导向下水循环冷却式射频消融治疗，联合治疗后第1、3个月行螺旋 CT 双期增强扫描评价疗效。结果肿瘤影像学评价，完全缓解（complete remission，CR）11个，部分缓解（partial remission，PR）24个，稳定（no change，NC）5个，进展（progressive disease，PD）1个。32例随访10～22个月，31例存活，1例术后13个月因上消化道大出血死亡。结论 TACE 联合 CT 引导下水循环冷却式 RFA 是治疗原发性肝癌安全、微创、有效的方法。
Objective To analyze the clinical efficacy of transcatheter arterial chemoembolization （TACE）combined with CT-guided water circulatory-cooling radiofrequency ablation （RFA）in the treatment of primary hepatocellular carcinoma. Methods A retrospective analysis was undertaken in 32 patients with 41 nodules of primary hepatocellular carcinoma from October 201 1 to August 2014.Seven nodules were less than 3.0 cm in diameter,6 nodules between 3.0 -4.0 cm,9 nodules between 4.0 -5.0 cm,and 19 larger than 5.0 cm.All the patients were treated by TACE combined with CT-guided water circulatory-cooling RFA.All the patients underwent follow-up with enhanced CT scanning after 1 and 3 months. Results According to the results of the CT scanning,there were 1 1 complete remission （CR）,24 partial remission （PR）,5 no change （NC）and 1 progressive disease （PD）in all of the nodules.Follow-up reviews for 10 -22 months in the 32 patients showed 31 survived and 1 patient died of upper gastrointestinal bleeding. Conclusion TACE combined with CT-guided water circulatory-cooling RFA is a safe,minimal invasive and effective method in the treatment of primary hepatocellular carcinomas.
出处
《中国微创外科杂志》
CSCD
北大核心
2015年第10期883-886,903,共5页
Chinese Journal of Minimally Invasive Surgery
关键词
肝细胞肝癌
化疗栓塞
射频消融
Hepatocellular carcinoma
Chemoembolization
Radiofrequency ablation
