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肝动脉栓塞化疗联合CT导向射频消融术治疗中、晚期肝癌的评价 被引量:111

Combination of transcatheter arterial chemoembolization and CT-guided radiofrenquency ablation in treating advanced hepatocellular carcinoma
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摘要 目的 探讨肝动脉栓塞化疗联合CT导向下的射频消融治疗中、晚期原发性肝癌的疗效。方法  85例中、晚期原发性肝癌患者按单双日法分组原则分为A、B 2组。A组 :经导管肝动脉栓塞化疗组 (TACE组 ) ,共 4 3例 ;B组 :肝动脉栓塞化疗联合CT导向下的射频消融治疗组 (联合治疗组 ) ,共 4 2例。结果 TACE组的完全坏死率、初次复发率及 1年存活率分别 2 0 .93%、39.5 3%和79 0 7% ;而联合治疗组分别为 92 .86 %、9.5 3%和 97.6 2 %。两组间完全坏死率、初次复发率及 1年生存率的差异皆有显著性意义 (其相应P值分别为 0 .0 0 1,0 .0 0 4 ,0 .0 0 9)。 Objective To investigate the therapeutic effect of transcatheter arterial chemo-embolization (TACE) combined with CT-guided percutaneous radiofrequency ablation (RFA) in treating advanced primary hepatocellular carcinoma. Methods Eighty-five cases with advanced primary hepatocellular carcinoma were randomly divided into group A and group B. In group A, 43 cases were treated with TACE, and in group B, 42 cases were treated with TACE and RFA. Results The complete necrosis rate of tumor, the recurrence rate, and one-year survival rate were 20 93%, 39.53%, and 79 07%, respectively in group A, and 92.86%?9.53%, and 97.62%, respectively in group B. There were significant statistical differences between the two groups (P value were 0.001, 0.004, and 0 009, respectively). Conclusion The therapeutic effects of TACE combined with CT-guided RFA show better results than that of TACE alone.
出处 《中华放射学杂志》 CAS CSCD 北大核心 2003年第10期901-904,共4页 Chinese Journal of Radiology
关键词 肝动脉栓塞化疗 CT导向 射频消融术 联合治疗 中期 肝癌 晚期 Carcinoma, hepatocellular Chemoembolization, therapeutic Radiofrequency Evaluation studies
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