摘要
收集过敏性紫癜(HSP)患儿56例,探讨不同分组血清IgA1及其低糖基化水平与临床症状的相关性。结果显示HSP轻度组患儿血清IgA1水平及蚕豆凝集素和IgA1结合力低于重度组,差异有统计学意义(P<0.05);轻度与中度组差异无统计学意义;HSP患儿血清IgA1水平增高且存在低糖基化,其血清异常IgA1水平可能与病情轻重、蛋白尿严重程度相关。
56 cases of Henoch-Schonlein purpura in children were collected, to investigate the level of serum IgA1 and galactose-deficient IgA1 in different groups. At the same time, to explore the correlation between clinical symp-toms and the level of serum IgA1 and galactose-deficient IgA1 . The results showed that the group with mild levels of serum IgA1 and IgA1 binding force vicia villosa lectin was lower than the severe group, and the difference was sta-tistically significant （ P 〈0. 05 ）; there was no significant difference between the mild group and the moderate group. Henoch-Schonlein purpura with the serum IgA1 had increased,and they had low galactose. The levels of ga-lactose-deficient IgA1 may be associated with the severity of the disease and proteinuria.
出处
《安徽医科大学学报》
CAS
北大核心
2015年第10期1513-1515,共3页
Acta Universitatis Medicinalis Anhui
基金
安徽省自然科学基金(编号:11040606M168)
关键词
过敏性紫癜
儿童
IGA1
低糖基化
Henoch-Schonlein purpura
children
galactose-deficient
