摘要
目的观察阿昔洛韦联合加巴喷丁治疗带状疱疹神经痛的临床疗效及安全性。方法将130例带状疱疹患者随机分为对照组与观察组(每组65例),两组均给予阿昔洛韦抗病毒治疗,观察组加用加巴喷丁治疗。采用视觉模拟评分法(VAS)对两组患者的治疗效果进行评价。结果治疗后两组的疼痛程度、疼痛发生率均有不同程度的改善,两组比较P<0.05,差异有统计学意义,观察组改善更为明显。结论阿昔洛韦联合加巴喷丁可较快缓解带状疱疹所致神经痛,降低带状疱疹后遗神经痛(PHN)的发生,且不良反应发生率低。
Objective To observe the clinical curative effect of acyclovir plus gabapentin on herpes zoster neuralgia and the safety. Methods 130 cases with herpes zoster were randomly divided into 2 groups：control group and observation group, 65 in each;antiviral therapy with acyclovir was given to cases in both groups while gabapentin capsule was added to cases in observation group;VAS was ap-plied in the evaluation of the curative effect in the 2 groups. Results After treatment, certain improvement of the pain degree and the oc-currence of pain was found in the cases in both groups, the improvement in observation group was more obvious, and the difference be-tween the 2 groups was of statistical significance （P〈0.05）. Conclusions Acyclovir plus gabapentin can relieve the neuralgia caused by herpes zoster and decrease the occurrence of post-herpetic neuralgia （PHN） and the occurrence of side effect is lower.
出处
《西南军医》
2015年第5期495-497,共3页
Journal of Military Surgeon in Southwest China
