摘要
目的 分析某省某市人乳头瘤病毒（HPV）感染及亚型分布情况。方法 以2014年7月-2015年7月本院妇科就诊的1 000例患者为研究对象,采用定量聚合酶链反应（PCR荧光法）检测HPV感染情况,并采用导流杂交技术检测其亚型。结果 （1）1 000例患者妇女中HPV阳性感染率为20%（200/1 000）;（2）不同年龄段阳性率之间具有统计学意义（P〈0.05）,阳性率最高的为31-40岁和41-50岁;（3）不同年龄段阳性构成比之间具有统计学意义（P〈0.05）,阳性患者主要集中在31-40岁和41-50岁;（4）高危型HPV感染亚型主要以HPV-52、HPV-58、HPV-53、HPV-16和HPV-18。结论 HPV感染检测可为宫颈癌的早期诊断、预防及疗效观察提供依据,具有重要临床意义。
Objective To analyze the distribution of human papil omavirus（HPV）infection and subtype in a province. Methods From July 2014 to July 2015, 200 patients in our hospital gynecology clinic for study,used quantitative polymerase chain reaction（PCR assay）seized Measured HPV infection,and the used of flow-through hybridization to detect HPV subtypes. Results（1）200 patients with HPV-positive women in the infection rate was 29.5%（59/200）.（2）It was statistical y significant（P〈0.05）between the different age groups positive rate,positive rate for 31-40 year-old and 41-50 years old,statistical y significant（P〈0.05）.（3）Different ages positive constituent ratio positive patients were mainly concentrated in the 31-40 years and 41-50 years old.（4）High-risk HPV subtype infection mainly HPV-52,HPV-58,HPV-53,HPV-16 and HPV-18. Conclusion HPV infection detection can provide the basis for the diagnosis,prevention and therapeutic early cervical cancer has great clinical significance.
出处
《中国卫生标准管理》
2015年第25期8-9,共2页
China Health Standard Management
