摘要
目的:探讨脑室周围白质软化症临床CT特征。方法:对83例脑室周围白质软化症患者临床CT资料进行回顾性分析。结果:脑室旁软化灶型14例,其中位于双侧枕角旁5例;右侧脑室体部及前、后角旁各2例;左侧脑室体旁3例,枕角旁2例,同时伴有软化灶旁白质减少和皮层灰质变薄;弥漫性白质减少型69例,其中发生于枕角旁39例,前、后角旁15例,弥漫性白质减少15例;合并脱髓鞘病灶7例,胼胝体发育不良19例。CT表现为脑室旁见斑点状或条索状软化灶,个别病例呈球囊状改变;双侧脑室前、后角旁白质容量减少,重者半卵圆中心残留少量白质,枕角呈直角状扩大,边缘僵直,灰质层逼近脑室外侧缘。统计结果表明不同孕期胎龄生产史对病变类型的分布有差异(χ2=52.28,P<0.05),弥漫性白质减少分布部位与孕期胎龄生产史间有差异(χ2=25.89,P<0.05)。围产期脑白质损伤严重程度与胎龄有相关,孕期胎龄愈小,脑白质损伤愈严重。结论 :脑室周围白质软化症具有特征性,CT检查能够清楚地显示脑白质损伤的病理解剖形态。
Objective： To investigate the CT characteristics of periventricular leukomalacia. Methods： The clinical CT findings of 83 cases of periventricular leukomalacia were retrospectively analyzed. Results： Fourteen cases of the softening le- sions type near cerebral ventricle included 5 cases of beside the bilateral occipital horn, 2 cases of body and anterior horn near posterior horn of right lateral ventricle, 3 cases of beside left lateral ventricle body, 2 cases of near occipital horn, and accompanied by white matter reduction beside softening lesions and cortical gray matter thinning. 69 cases of the diffuse white matter reduction type included 39 cases of near the occipital horn, 15 cases of anterior horn near posterior horn, 15 cases of diffuse white matter reduction. There were 7 cases of merging demyelinating lesions type and 19 cases of agenesis of corpus callosum. CT showed mottling or funicular malacia lesions around cerebral ventricle. Individual cases presented the ball cystic changes. The white matter capacity near anterior horn or posterior horn of dual lateral ventricle reduced, severely centrnm semiovale had residual small area white matter. The occipital horns showed right angle shaped enlargement, the stiff edge, gray matter layer approaching the outer edge of the cerebral ventricle. Statistical results confirmed the production history of different pregnancy gestational age have a difference for the distribution of the lesion types （χ2=52.28, P〈0.05）, the distribution position of diffuse white matter reduction have a difference with production history of pregnancy gestational age （χ2=25.89, P〈 0.05）. Brain white matter injury severity in perinatal related to gestational age, smaller gestational age in pregnancy, the more severe white matter injury. Conclusions： Periventricular leukomalacia have certain feature, pathological anatomy morphology of the cerebral white matter injury can been clearly displayed by CT.
出处
《中国临床医学影像杂志》
CAS
北大核心
2015年第9期612-615,共4页
Journal of China Clinic Medical Imaging
