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磁共振弥散张量成像对正常大脑白质纤维束构象的初步研究 被引量:8

Preliminary study of MR diffusion tensor imaging in cerebral white matter fiber tracts
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摘要 目的利用磁共振弥散张量成像(DTI)研究正常成人脑内各部位各向异性程度及正常白质纤维束构象特征。方法对25名正常志愿者进行常规MR及DTI序列检查,重建FA图及三维彩色编码张量图。分别在半卵圆中心、基底节区和大脑脚层面测量主要白质束的FA值。结果DTI显示灰质与白质区各向异性存在显著差异,不同部位的白质纤维束各向异性程度亦不相同,且左右两侧基本对称,重建FA图和三维彩色编码张量图可显示白质内大部分主要的白质纤维束。结论DTI可清晰显示脑内白质纤维束的走行及分布,为了解脑功能与白质通路间关系提供了有力研究手段。 Objective To study the degree of anisotropy in different cerebra l regions and the architecture of white matter fiber tracts with MR diffusion tens or imaging (DTI). Methods Diffusion tensor images were obtained from 25 voluntee r who underwent clinical MR imaging and were found to have no abnormalities on c onventional MR images. Color-coded FA images and three-dimensional color-code d tensor images were reconstructed. Fractional anisotropy (FA) were measured in some main white matter structures of peripheral white matter, basal ganglia, cer ebral peduncle etc. Results Anisotropy measurements in white matter regions were significantly differ from gray matter regions. Different white matter structure s shown different anisotropy degree,reconstructed FA images and three-dimensio nal color-coded tensor images can display main white matter fibral.Conclusions DTI can show the orientation and distribution of cerebral white matter fiber tra cts. It is very helpful to study the relationship between cerebral functions and white matter fiber crossings.
出处 《实用医学影像杂志》 2005年第2期61-64,共4页 Journal of Practical Medical Imaging
关键词 磁共振成像 弥散张量成像 白质纤维束 Magnetic resonance image Diffusion tensor imaging White matter fiber tracts
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