慢阻肺Ⅰ号方治疗慢性阻塞性肺疾病急性加重期(痰热壅肺证)的疗效观察被引量：20

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摘要目的观察慢阻肺Ⅰ号方治疗慢性阻塞性肺疾病(COPD)急性加重期患者(痰热壅肺证)的临床疗效。方法将80例患者随机分为两组,每组40例。两组均给予西医基础治疗,治疗组加服中药方剂慢阻肺Ⅰ号方,疗程均为14 d,分别于治疗前1 d和治疗后14 d比较两组患者证候总积分、实验室检查指标以及有效率。结果两组中医证候总积分均明显降低,且治疗组明显低于对照组(P<0.05);治疗组总有效率为97.50%,高于对照组的87.50%(P<0.05);治疗后两组血液流变学指标、血浆IL-8、IL-17以及免疫球蛋白均较治疗前改善,治疗组改善幅度优于对照组(P<0.05);两组血浆LTB4、白细胞总数、中性粒细胞分类改善情况均较治疗前改善(P<0.05),组间差异无统计学意义(P>0.05)。结论慢阻肺Ⅰ号方治疗COPD急性加重期临床疗效确切,可明显改善患者临床症状以及实验室指标,提高患者生存质量。

作者许庆

机构地区山东省东昌府妇幼保健院

出处《中国中医急症》 2015年第9期1619-1621,共3页 Journal of Emergency in Traditional Chinese Medicine

关键词慢阻肺Ⅰ号痰热壅肺证慢性阻塞性肺疾病急性加重期

分类号 R725.6 [医药卫生—儿科]

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