1CENTER MM, J EMAL A, LORTET-TIEULENT J,et al. In- ternational variation in prostate cancer incidence and mortality rates[J]. Eur urol,2012,61(6) :1079-1092. 被引量：1
2SIEGEL R, NAISHADHAM D, JEMAL A. Cancer statistics, 2013[J]. CA Cancer J Clin,2013,63(1) : 11-30. 被引量：1
4HUGGINS C, HODGES CV, VALETT BS, et al. Studies on prostatic cancer: effect of castration of estrogen andofandroge- niniection on senlm phosphatases in metastatic carcinoma of the prostate[J]. Cancer Res, 1941,18 : 293-298. 被引量：1
5SAIGAL CS,GORE JL,KRUPSKI TL,et al. ADT increases car- diovascular morbidity in men with prostate cancer[J]. Cancer, 2007,110 (7) : 1493-1500. 被引量：1
6LU-YAO G, STUKEL TA, YAO SI. Changing patterns in com- peting causes of death in men with prostate cancer:a population based study[J]. J Urol,2004,171(6 Pt 1):2285 -2290. 被引量：1
7GOLDENBERG SL, BRUCHOVSKY N, GLEAVE ME, et al. Intermittent androgen suppression in the treatment of prostate cancer : a preliminary report[J]. Urology, 1995,45 (5) : 839-844. 被引量：1
8BUHLER KR, RICHARD A, ROYAI RA, et al. Intermittent androgen suppression in tb.e LuCaP 23,12 prostate cancer xeno graft model[J]. Prostate, 2000,43(1) :63-68. 被引量：1
9RUSSO P, LIGUORI G, HESTON WD. et al. Effects of inter mittent diethylstilbestrol diphosphate administration on the R3327 rat prostatic carcinoma [J]. Cancer Res, 1987, 47 (22) :5967-5971. 被引量：1
10AKAKURA K, BRUCHOVSKY N, GOLDENBERG SL, et al. Effects of intermittent androgen suppression on androgen de- pendent tumors. Apoptosis and serum prostate specific antigen[J]. Cancer, 1993,71(9) :2782-2790. 被引量：1
3Huggins C,Stevens RE,Hedges CV.Studies on prostatic cancer:2.The effects of castration on advanced carcinoma of the prostate gland[J].Arch Surg,1941,43(2):209-223. 被引量：1
4Isaacs JT,Coffey DS.Adaption versus selection as the mechanism responsible for relapse of prostatic cancer to androgen ablation therapy as studied in dunning R-3327-H adenocarcinoma[J].Cancer Res,1981,41(12 Pt 1):5070-5075. 被引量：1
5Feldman BJ,Feldman D.The development of androgen-independent prostate caner[J].Nat Rev Cancer,2001,1(1):34-45. 被引量：1
6Goldenberg SL,Bruchovsky N,Gleave ME,et al.Intermittent androgen suppression in the treatment of prostate cancer:a preliminary report[J].Urology,1995,45(5):839-845. 被引量：1
7Akakura K,Bruchovsky N,Rennie PS,et al.Effects of intermittent androgen suppression on the stem cell composition and the expression of the TRPM-2(clusterin)gene in the Shionogi carcinoma[J].J Steroid Biochem Mol Biol,1996,59(5-6):501-511. 被引量：1
8Sato N,Gleave ME,Bruchovsky N,et al.Intermittent androgen suppression delays progression to androgen-independent regulation of prostate-specific antigen gene in the LNCaP prostate tumor model[J].J Steroid Biochem Mol Biol,1996,58(2):139-146. 被引量：1
9Buhler KR,Santucci RA,Royai RA,et al.Intermittent androgen suppression in the LuCaP 23.12 prostate cancer xenograft model[J].Prostate,2000,43(1):63-70. 被引量：1
10Calais da Silva FE,Calais da Silva FM,Goncalves F,et al.Phase Ⅲ Study of intermittent monotherapy versus continuous combined androgen deprivation[J].Eur Urol,2007,6(2 Suppl):28. 被引量：1
