摘要
目的研究宫颈上皮内瘤变(CIN)患者支原体感染情况及耐药分析,为临床诊治提供依据。方法采用回顾性方法对523例宫颈上皮内瘤变(CIN)患者的分泌物进行解脲支原体(Uu)和人型支原体(Mh)培养及药敏试验。结果 523例宫颈上皮内瘤变患者Uu的检出率为55.25%(289例),Uu和Mh混合感染的检出率为13.58%(71例),检出5例单一Mh感染的患者。对抗菌药物敏感率高的是强力霉素(91.16%)、美满霉素(90.48%),其次是交沙霉素(81.29%)、克拉霉素(75.85%),对氧氟沙星的敏感率最低,仅为10.20%。结论宫颈上皮内瘤变患者中支原体感染存在普遍,应合理使用抗菌药物治疗,支原体感染与宫颈上皮内瘤变的发生可能密切相关。
Objective To explore the infection and antimicrobial resistance of mycoplasma in cervical intraepithelial neoplasia patients. Methods Retrospective analysis was performed on 523 specimens from cervical intraepithelial neoplasia（ CIN） patients; The specimens were cultured for detection of U. urealyticum（ Uu） and M. hominis（ Mh） and their drug sensitivity. Results In the 523 cases with cervical intraepithelial neoplasia,289 were Uu positive（ 55. 25%）,71 cases were both Uu and Mh positive,and 5 cases were Mh positive. The sensitivity of the pathogens was 91. 16% to Deoxyeyeline,90. 70% to Minoem,81. 29% to Josamyem,and 75. 72% to Clarithromycin. The lowest sentivity was 10. 27% to Ofloxacin. Conclusion Mycoplasma infections widely exist in CIN patients,which may be closely associated with CIN. Antibiotics should be used rationally.
出处
《中国微生态学杂志》
CAS
CSCD
2015年第9期1094-1095,1116,共3页
Chinese Journal of Microecology
关键词
宫颈上皮内瘤变
支原体属
感染率
药敏试验
Cervica lintraepithelial neoplasia
Mycoplasma
Infection rate
Drug sensitivity test
