摘要
目的探讨血清唾液酸在Ⅱ型糖尿病视网膜病变不同阶段的作用关系。方法 54例Ⅱ型糖尿病患者纳入本研究作为观察组,另设健康对照组54例,观察比较不同程度糖尿病视网膜病变患者和健康对照组之间血清唾液酸浓度、血糖、血脂。结果两组患者血脂无差异(P>0.05),观察组血糖和血清唾液酸水平均较对照组高,且唾液酸水平与视网膜病变程度呈正相关(P<0.05)。结论血清唾液酸浓度增加与2型糖尿病视网膜病变各阶段之间有关联,可以用于视网膜病变的诊断和预后监测。
【Objective】To explore the variation of serum sialic acid at different stages of type 2 diabetic retinopathy.【Methods】54 cases of type 2 diabetes patients included in this study,separate the healthy control group（54 cases）,compared the serum sialic acid concentration, blood glucose, blood lipid between different degrees of diabetic retinopathy patients and healthy control group. 【Results】There was no different in blood lipid（P〉0.05）, the blood glucose and serum sialic acid levels were higher in observer group than control group, and sialic acid levels was positively correlated with retinopathy severity（P〈0.05）. 【Conclusion】Serum sialic acid concentration increases were associated with each stage of type 2 diabetic retinopathy, can be used for diagnosis and prognosis monitoring retinopathy.
出处
《中国医学工程》
2015年第8期9-10,共2页
China Medical Engineering
基金
深圳市科技研发资金项目知识创新计划(JCYJ2013 0401111359353)
