摘要
目的:探讨血清唾液酸和糖尿病性视网膜病变几个阶段之间潜在的关联。方法:1型糖尿病视网膜不同程度病变组40例。对照组30例,对其血清唾液酸水平进行研究。结果:结果显示,研究组与对照组相比有较高的血清唾液酸浓度(95.95±9.5 vs 45.05±19.91mmoL/L,P=0.0001)。我们也观察到糖尿病性视网膜病变的水平逐步上升,其浓度升高(P<0.05),但相关性较弱。血清唾液酸浓度与血糖浓度呈正相关(r=0.67,P=0.0001)。结论:血清唾液酸浓度的增加与视网膜病变阶段有关。这对确定1型糖尿病患者视网膜病变的程度有帮助。但是,仍然需要更详细的研究,以得到更精确的结论。
AIM： To i serum sialic grades. METHODS nvestigate the potential association between acid and diabetic retinopathy and its several We studied the level of serum sialic acid in70 patients. Thirty control vs 40 type 1 diabetics and with different levels of diabetic retinopathy as well. RESULTS. We found higher levels of serum sialic acid level in diabetics compared to control subjects （95.95±9.5 vs 45.05±19.91 mmoL/L, P= 0. 0001 ）. We also observed a progressive rise in its concentration as the level of diabetic retinopathy increased （ P〈 0.05） but the correlation was weak. Serum sialic acid level correlated positively with blood glucose level （ r= 0.67, P= 0. 0001 ）. CONCLUSION： Increase in serum sialic acid levels seems to be related to the stage of the retinopathy and may help us to determine the extent of retinopathy in type 1 diabetic patients. But we think that we need more detailed studies to get a more precise conclusion.
出处
《国际眼科杂志》
CAS
2013年第10期1950-1952,共3页
International Eye Science
基金
马尔马拉大学科学研究委员会资助~~
