摘要
目的探讨体素内不相干运动成像(IVIM)在原发性直肠癌术前检查中的价值。方法采用3.0T MR扫描仪IVIM序列(b=0、25、50、75、100、150、200、400、600、800、1000、1200、1500、2000s/mm2)和T2cube序列获得62例直肠癌患者术前的影像资料。测量和比较正常肠壁与肿块、不同分化程度直肠癌的ADC、D*、D和f值;评价IVIM中不同b值的DWI图像的SNR和CNR。结果直肠癌肿块的ADC、D、D*和f值均明显小于正常肠壁(P均<0.05);中、低分化直肠癌ADC值差异有统计学意义(F=31.92,P=0.01),高、中、低分化直肠癌D值差异有统计学意义(F=16.79,P=0.03);b=1000s/mm2时的DWI图像质量最好,肿块与正常肠壁显示最佳。结论 IVIM图像可提供肿瘤ADC、D、D*和f值的信息,可在一定程度上反映肿瘤的病理生理状态,其中D值较ADC值更能够准确地反映直肠癌组织间分化程度的差别,在b=1000s/mm2时图像质量最佳,有利于发现直肠癌病灶和了解术前肿瘤的分化程度。
Objective To evaluate the clinical value of intravoxel incoherent motion imaging（IVIM）in diagnosis of rectal carcinoma.Methods Sixty-two patients with rectal carcinoma underwent IVIM（b=0,25,50,75,100,150,200,400,600,800,1000,1200,1500 and 2000s/mm2）at 3.0T MR scanner were enrolled.The ADC,D,D＊and f values were measured and calculated in IVIM sequence;all patients were divided into high,medium and low differentiation,and the ADC,D,D＊and f values were compared respectively.The different b values images of IVIM were evaluated by SNR and CNR.Results The ADC,D,D＊and f values of rectal tumor showed significant reduction compared with those of normal rectal wall（all P〈0.05）;the difference of ADC value in medium differentiation and low differentiation were statistically significant（F=31.92,P=0.01）;the difference of D value in high,medium and low differentiation were statistically significant（all P〈0.05）,but of D＊and f value were not statistically significant（F=16.79,P=0.03）.The best b value of diffusion weighted images in IVIM sequence were 1000s/mm2.Conclusion IVIM can reveal ADC,D,D＊and f values of rectal carcinoma,which is useful for demonstrating the pathophysiology process of rectal cancer.D value is more significant than ADC value in histology differentiation.The optimal images are shown in b=1000s/mm2.
出处
《中国医学影像技术》
CSCD
北大核心
2015年第9期1349-1353,共5页
Chinese Journal of Medical Imaging Technology
基金
粤澳两地靶向定位多b值弥散加权成像及PET/CT-MR评估原发性直肠癌淋巴结转移的研究(2013B051000058)
关键词
结直肠肿瘤
磁共振成像
体素内不相干运动成像
Colorectal neoplasms
Magnetic resonance imaging
Intravoxel incoherent motion imaging
