摘要
目的观察比较丙泊酚与咪达唑仑在脑出血手术中的麻醉效果及护理措施。方法选取128例行脑出血手术的患者,随机分为对照组和观察组,每组64例。对照组给予丙泊酚麻醉,观察组给予咪达唑仑麻醉,术后进行护理干预,包括心理护理、饮食护理等。结果手术后,两组患者心率显著升高,且观察组心率显著高于对照组(P<0.05);两组患者平均动脉压显著降低,且观察组显著低于对照组(P<0.05)。丙泊酚维持血红蛋白稳定性、氧摄取率方面均优于咪达唑仑(P<0.05);观察组患者术后格拉斯哥预后(GOS)评分较对照组升高明显(P<0.05);两组患者日常生活能力(ADL)评分间未见显著差异(P>0.05)。结论丙泊酚可有效改善脑出血患者的脑氧合能力,降低血管阻力,改善患者血压状况,且麻醉效果更佳,能显著改善患者近期预后,结合护理干预可取得更优的效果,值得临床推广。
Objective To investigate the effect of ProPofol and midazolam in cerebral hemorrhage surgery and nursing measures. Methods Totally 128 Patients with cerebral hemorrhage routine surgery were randomly divided into the control grouP and the observation grouP, 64 cases in each grouP. The control grouP received ProPofol anesthesia, the observation grouP were given midazolam anesthesia. Results The HR in the two grouPs were significantly increased and the observation grouP increased more significantly （ P 〈 0. 05 ） , Patients MAP were both significantly decreased and the observation grouP decreased more significantly （ P 〈 0. 05 ） . ProPofol in maintaining the stability of hemoglobin was suPerior than midazolam （ P 〈 0. 05 ） . The PostoPerative GOS score of the observation grouP increased more significantly than the control grouP （ P 〈 0. 05 ） , and ADL scores of the two grouPs had no significant difference （ P〉 0. 05 ） . Con-clusion ProPofol can effectively imProve cerebral oxygenation in Patients with cerebral hemorrhage, reduce vascular resistance, imProve blood Pressure can achieve better results, and is worth of clinical aPPlication.
出处
《中国药业》
CAS
2015年第17期103-104,共2页
China Pharmaceuticals
关键词
脑出血
丙泊酚
咪达唑仑
护理
cerebral hemorrhage
ProPofol
midazolam
nursing
