摘要
目的探讨帕金森病（PD）患者泌尿系统障碍的发病特点及影响因素。方法收集76例PD患者临床资料并分析泌尿系统障碍的发病特点，对76例PD患者行SCOPA—AUT泌尿系统部分评分，并与PD患者的性别、年龄、帕金森病评价量表（UPDRS）、Hoehn—Yahr（H—Y）分期、病程、疲劳严重度量表（FSS）评分、美多芭剂量、受教育程度进行Spearman相关性分析。结果76例PD患者中存在泌尿系统障碍者37例，发病率为48．9％，泌尿系统障碍组PD患者的UPDRS评分、FSS评分、病程比非障碍组高（均P〈0．05），PD患者泌尿系统障碍与患者的UPDRS评分、H—Y分期、FSS评分、病程有关（r=0．607～0．812，均P〈0．05）。结论PD患者的泌尿系统障碍发生率较高，影响因素较多。
Objective To explore the characteristics of urinary disorders in patients with Parkinson＇s disease （PD） and influential factors involved. Methods Clinical data were collected from 76 PD patients in our hospital to analyze the characteristics of urinary disorders. They were scored using the Scales for Outcomes in Parkinson＇s Disease - Autonomic questionnaire SCOPA- AUT （part of urinary disorders）. Then Spearman＇s correlation analysis was performed between SCOPA- AUT scores and gender, age, the Unified Parkinson＇s Disease Rating Scale （UPDRS） scores, Hoehn- Yahr （ H - Y） stage, duration of disease, the Fatigue Severity Scale （FSS） scores, levodopa doses and education background. Results There were 37 PD patients with urinary disorders （37/76, 48.9% ）. They produced higher scores of UPDRS and FSS, and longer duration of disease than PD patients without urinary disorders （ all P 〈0. 05 ）. A positive correlation was determined between SCOPA - AUT scores and UPDRS scores, H - Y stage, FSS scores and duration of disease （ r = 0. 607 - 0.812, all P 〈0. 05 ）. Conclusion PD patients have a higher incidence of urinary disorders, which is associ- ated with multiple factors.
出处
《徐州医学院学报》
CAS
2015年第7期441-443,共3页
Acta Academiae Medicinae Xuzhou
基金
国家自然科学基金（81301077）
徐州市社会发展科技计划基金（XM138058）
关键词
帕金森病
泌尿系统障碍
相关性
Parkinson＇s disease
urinary disorders
relationship
