摘要
目的探讨缺血性脑小血管病的危险因素在男、女不同性别患者中差异,为其防治提供参考依据。方法前瞻性研究2010年1月-2011年9月间在本院神经内科及康复科住院检查且病历资料完整,基于缺血性卒中分型系统TOAST分型确诊的缺血性脑小血管病患者160例,按照性别分为男性组与女性组,分析男性缺血性脑小血管病组和女性缺血性脑小血管病组两组患者危险因素的差异。结果缺血性脑小血管病患者160例,其中男性112例（70%）;女性48例（30%）,两者之比为2.375∶1。女性患者发病年龄高于男性患者,两者之间差异显著,有统计学意义（P〈0.05）,与男性缺血性脑小血管病患者相比,女性患者高血压发病率、吸烟、饮酒的发生率低于男性,两者之间差异显著,有统计学意义（P〈0.05）,女性患者高TC、高LDL发病率高于男性患者,两者之间差异显著,有统计学意义（P〈0.05）;与男性缺血性脑小血管病患者相比,女性患者在66岁∽75岁年龄段女性患者发病率高于男性,差异显著,有统计学意义（P〉0.05）。结论缺血性脑小血管病相关危险因素存在性别差异。
Objective To explore the gender differences of risk factors in different patients for male and female due to ischemic cerebral small vessel disease,to provide reference basis for its prevention and control. Methods Prospective study,select patients in rehabilitation department and neurology Department of Xingtai People＇s Hospital from 2010. 1 to2011. 9,clinical confirmed,based on ischemic stroke classification system TOAST typing diagnosis. Results 160 cases due to ischemic cerebral small vessel disease,112 males（ 70%）,48 female cases（ 30%）. The ratio of both 2. 375∶ 1. Female patient age at onset was higher than the male patients,there was significant difference between the two groups,with statistical significance（ P〈0. 05）,compared with male patients due to ischemic cerebral small vessel disease,the hypertension prevalence,incidence of smoking,drink in female patients was lower than male patients,there was significant difference between the two groups,with statistical significance（ P〈0. 05）. Incidence of high LDL,TC of female patients was higher than male patients,there was significant difference between the two groups,with statistical significance（ P〈0. 05）. Compared with male patients due to ischemic cerebral small vessel disease,morbidity of female patient with 66 ∽ 75 year-old was higher than male,there was significant difference between the two groups,with statistical significance（ P〈0. 05）. Conclusion There were some gender differences in risk factors for ischemic cerebral small vessel disease.
出处
《中风与神经疾病杂志》
CAS
北大核心
2015年第8期695-698,共4页
Journal of Apoplexy and Nervous Diseases
关键词
缺血性脑小血管病
危险因素
性别
Ischemic cerebral small vessel disease
Risk factors
Gender
