摘要
目的回顾分析77例溃疡性结肠炎(UC)患者的临床资料和随访情况以指导并完善UC的诊治。方法收集该院2009年11月至2014年10月住院治疗的77例UC患者临床资料并电话随访一部分患者维持治疗情况。结果活动期UC患者中度活动者占69.9%,病变范围以左半结肠(46.6%,34/73)及广泛结肠(50.7%,37/73)为主。UC主要临床表现为腹痛、腹泻、黏液脓血便及便血等。肠镜下UC活动期主要表现为肠黏膜充血、肿胀、糜烂及浅溃疡形成,内镜下组织活检多表现为黏膜慢性炎症和(或)糜烂。UC患者病情越重,相对应的血清清蛋白平均值越低。治疗上以氨基水杨酸制剂、糖皮质激素及免疫抑制剂为主。氨基水杨酸制剂是长期维持治疗药物,UC总体治疗有效率为89.0%(55/73)。结论 UC治疗方案基本遵循共识意见,仍需加强UC随访。
Objective T9 analyze the clinical characteristics, therapy and follow-up of the patients with ulcerative coitus （UC）. Methods Collect the date of 77 inpatients with UC at the Second Affiliated Hospital of Chongqing Medical University between November,2009 and october,2014,and assigned the patients randomly. Results 69.9% of the patients who were in the activity stage were moderate severity. E2 （46.6 %, 34/73）and E3 （50.7 %, 37/73）were the common lesions range. The main clinical manifestations were abdominal pain, diarrhea,mucopurulent bloody stool and bloody stool. The enteroscopy mostly showed that intestinal mucosa hyperemia, eddma, erosion, and small ulcers had the common features of UC. The common biopsy results were chronic inflammation and/or erosion. The average value of serum ALB decreases while the severity of UC patients increases. Drug therapy was the main treatment of UC. The maintenance therapy was aminosalicylic acid, the effective ratio of treatment is 89.0 % （55/ 73）. Conclusion UC treatment plan basically follow the consensus and we should enhance the follow-up of UC patients.
出处
《重庆医学》
CAS
北大核心
2015年第25期3517-3519,共3页
Chongqing medicine
关键词
结肠炎
溃疡性
临床表现
随访研究
coliti, ulceratives
clinical manifestations
follow-up studies
